首页> Chinese medicine> Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model.

Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model.

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第一作者： Jingtao,Wu

第一单位： Department of Orthopaedics, Wenzhou Key Laboratory of Perinatal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China.;Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou, 325000, Zhejiang Province, China.;The Second School of Medicine, Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China.

作者： Jingtao,Wu ^[1] ; Heng,Yu ^[1] ; Yangcan,Jin ^[1] ; Jingquan,Wang ^[1] ; Liwen,Zhou ^[2] ; Teng,Cheng ^[1] ; Zhao,Zhang ^[1] ; Binghao,Lin ^[1] ; Jiansen,Miao ^[1] ; Zhongke,Lin ^[3]

作者单位： Department of Orthopaedics, Wenzhou Key Laboratory of Perinatal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China.;Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou, 325000, Zhejiang Province, China.;The Second School of Medicine, Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China. ^[1] The First School of Medicine, Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China. ^[2] Department of Orthopaedics, Wenzhou Key Laboratory of Perinatal Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China. zhongkelinspine@163.com.;Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou, 325000, Zhejiang Province, China. zhongkelinspine@163.com.;The Second School of Medicine, Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China. zhongkelinspine@163.com. ^[3]

关键词 Ajugol Autophagy DMM ER stress Osteoarthritis TBHP TFEB

DOI 10.1186/s13020-023-00824-7

PMID 37679844

发布时间 2023-11-23

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