Mammalian autophagosomes form from finger-like phagophores.

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作者： Claudia,Puri ^[1] ; Matthew J,Gratian ^[2] ; David C,Rubinsztein ^[3]

作者单位： Department of Medical Genetics, University of Cambridge, Cambridge, UK; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK; UK Dementia Research Institute, Cambridge Biomedical Campus, University of Cambridge, The Keith Peters Building Cambridge, Hills Road, Cambridge CB2 0XY, UK. ^[1] Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. ^[2] Department of Medical Genetics, University of Cambridge, Cambridge, UK; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK; UK Dementia Research Institute, Cambridge Biomedical Campus, University of Cambridge, The Keith Peters Building Cambridge, Hills Road, Cambridge CB2 0XY, UK. Electronic address: dcr1000@cam.ac.uk. ^[3]

关键词 CHMP2A ESCRT complex RAB11A VPS4A autophagosome autophagy mitophagy phagophore recycling endosome superresolution microscopy

主题词动物(Animals);人类(Humans);自噬(Autophagy);内颗粒(Endosomes);细胞系(Cell Line);吞噬作用(Phagocytosis);哺乳动物(Mammals)

DOI 10.1016/j.devcel.2023.08.016

PMID 37683632

发布时间 2023-12-07

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