Overcoming Barriers Associated with Oral Delivery of Differently Sized Fluorescent Core-Shell Silica Nanoparticles.

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作者： Jacob A,Erstling ^[1] ; Nirmalya,Bag ^[2] ; Thomas C,Gardinier ^[3] ; Ferdinand F E,Kohle ^[1] ; Naedum,DomNwachukwu ^[1] ; Scott D,Butler ^[3] ; Teresa,Kao ^[2] ; Kai,Ma ^[4] ; Melik Z,Turker ^[1] ; Grant B,Feuer ^[1] ; Rachel,Lee ^[1] ; Nada,Naguib ^[2] ; James F,Tallman ^[1] ; Henry F,Malarkey ^[1] ; Lieihn,Tsaur ^[2] ; William L,Moore ^[1] ; Dana V,Chapman ^[5] ; Tangi,Aubert ^[1] ; Saurabh,Mehta ^[1] ; Richard A,Cerione ^[1] ; Robert S,Weiss ^[1] ; Barbara A,Baird ^[6] ; Ulrich B,Wiesner ^[3]

作者单位： Department of Materials Science and Engineering, Cornell University, Ithaca, NY, 14853, USA. ^[1] Department of Biomedical Engineering, Cornell University, Ithaca, NY, 14853, USA. ^[2] Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, USA. ^[3] Department of Biomedical Sciences, Cornell University, Ithaca, NY, 14853, USA. ^[4] Department of Applied and Engineering Physics, Cornell University, Ithaca, NY, 14853, USA. ^[5] Center for Precision Nutrition and Health, Division of Nutritional Sciences, Cornell University, Ithaca, NY, 14853, USA. ^[6] Kavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, NY, 14853, USA. ^[7]

关键词 Caco-2 permeability imaging fluorescence correlation spectroscopy mucus diffusion nanoparticle oral delivery nanoparticle pill formulation