Acetylcholinesterase inhibition protects against trastuzumab-induced cardiotoxicity through reducing multiple programmed cell death pathways.

导出 OA

翻译打印收藏纠错

作者： Thawatchai,Khuanjing ^[1] ; Chayodom,Maneechote ^[2] ; Benjamin,Ongnok ^[3] ; Nanthip,Prathumsap ^[1] ; Apiwan,Arinno ^[3] ; Titikorn,Chunchai ^[1] ; Busarin,Arunsak ^[2] ; Siriporn C,Chattipakorn ^[3] ; Nipon,Chattipakorn ^[1]

作者单位： Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. ^[1] Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. ^[2] Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand. ^[3] Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai, 50200, Thailand. ^[4] Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. nchattip@gmail.com. ^[5] Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. nchattip@gmail.com. ^[6] Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand. nchattip@gmail.com. ^[7]

关键词 Acetylcholinesterase inhibitor Cardiotoxicity Mitochondria Programmed cell death pathways Trastuzumab

主题词男(雄)性(Male);动物(Animals);大鼠(Rats);大鼠, Wistar(Rats, Wistar);乙酰胆碱酯酶(Acetylcholinesterase);细胞凋亡(Apoptosis);炎症(Inflammation)

DOI 10.1186/s10020-023-00686-7

PMID 37691124

发布时间 2023-11-23

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交