Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude.
第一作者:
Latha,Kadalayil
第一单位:
Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.;Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.
作者:
Latha,Kadalayil [1]
;
Md Zahangir,Alam [2]
;
Cory Haley,White [3]
;
Akram,Ghantous [4]
;
Esther,Walton [5]
;
Olena,Gruzieva [6]
;
Simon Kebede,Merid [7]
;
Ashish,Kumar [8]
;
Ritu P,Roy [9]
;
Olivia,Solomon [10]
;
Karen,Huen [10]
;
Brenda,Eskenazi [10]
;
Peter,Rzehak [11]
;
Veit,Grote [11]
;
Jean-Paul,Langhendries [12]
;
Elvira,Verduci [13]
;
Natalia,Ferre [14]
;
Darek,Gruszfeld [15]
;
Lu,Gao [16]
;
Weihua,Guan [17]
;
Xuehuo,Zeng [18]
;
Enrique F,Schisterman [19]
;
John F,Dou [20]
;
Kelly M,Bakulski [20]
;
Jason I,Feinberg [21]
;
Munawar Hussain,Soomro [22]
;
Giancarlo,Pesce [23]
;
Nour,Baiz [24]
;
Elena,Isaevska [25]
;
Michelle,Plusquin [26]
;
Marina,Vafeiadi [27]
;
Theano,Roumeliotaki [27]
;
Sabine A S,Langie [28]
;
Arnout,Standaert [29]
;
Catherine,Allard [30]
;
Patrice,Perron [31]
;
Luigi,Bouchard [32]
;
Evelien R,van Meel [33]
;
Janine F,Felix [34]
;
Vincent W V,Jaddoe [34]
;
Paul D,Yousefi [35]
;
Cecilia H,Ramlau-Hansen [36]
;
Caroline L,Relton [35]
;
Elmar W,Tobi [37]
;
Anne P,Starling [38]
;
Ivana V,Yang [39]
;
Maria,Llambrich [40]
;
Gillian,Santorelli [41]
;
Johanna,Lepeule [42]
;
Lucas A,Salas [43]
;
Mariona,Bustamante [40]
;
Susan L,Ewart [44]
;
Hongmei,Zhang [45]
;
Wilfried,Karmaus [45]
;
Stefan,Röder [46]
;
Ana Claudia,Zenclussen [46]
;
Jianping,Jin [47]
;
Wenche,Nystad [48]
;
Christian M,Page [49]
;
Maria,Magnus [50]
;
Dereje D,Jima [51]
;
Cathrine,Hoyo [52]
;
Rachel L,Maguire [53]
;
Tuomas,Kvist [54]
;
Darina,Czamara [55]
;
Katri,Räikkönen [54]
;
Tong,Gong [56]
;
Vilhelmina,Ullemar [56]
;
Sheryl L,Rifas-Shiman [57]
;
Emily,Oken [57]
;
Catarina,Almqvist [58]
;
Robert,Karlsson [56]
;
Jari,Lahti [54]
;
Susan K,Murphy [59]
;
Siri E,Håberg [50]
;
Stephanie,London [60]
;
Gunda,Herberth [46]
;
Hasan,Arshad [61]
;
Jordi,Sunyer [40]
;
Regina,Grazuleviciene [62]
;
Dana,Dabelea [63]
;
Régine P M,Steegers-Theunissen [37]
;
Ellen A,Nohr [64]
;
Thorkild I A,Sørensen [65]
;
Liesbeth,Duijts [66]
;
Marie-France,Hivert [67]
;
Vera,Nelen [68]
;
Maja,Popovic [25]
;
Manolis,Kogevinas [69]
;
Tim S,Nawrot [70]
;
Zdenko,Herceg [4]
;
Isabella,Annesi-Maesano [24]
;
M Daniele,Fallin [21]
;
Edwina,Yeung [71]
;
Carrie V,Breton [16]
;
Berthold,Koletzko [11]
;
Nina,Holland [72]
;
Joseph L,Wiemels [73]
;
Erik,Melén [74]
;
Gemma C,Sharp [75]
;
Matt J,Silver [76]
;
Faisal I,Rezwan [77]
;
John W,Holloway [78]
作者单位:
Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.;Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.
[1]
Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.;Department of Computer Science and Engineering, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh.
[2]
Merck Exploratory Science Center in Cambridge MA, Merck Research Laboratories, Cambridge, MA, 02141, USA.
[3]
Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.
[4]
Department of Psychology, University of Bath, Bath, UK.
[5]
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.;Centre for Occupational and Environmental Medicine, Region Stockholm, Sweden.
[6]
Centre for Occupational and Environmental Medicine, Region Stockholm, Sweden.
[7]
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
[8]
Helen Diller Family Comprehensive Cancer Center University of California, San Francisco, CA, 94143, USA.;Computational Biology and Informatics Core, University of California, San Francisco, CA, 94143, USA.
[9]
Children's Environmental Health Laboratory, University of California, Berkeley, CA, USA.
[10]
Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany.
[11]
CHC, St Vincent, Liège-Rocourt, Belgium.
[12]
Department of Pediatrics, Vittore Buzzi Children Hospital, University of Milan, Milan, Italy.
[13]
Pediatric Nutrition and Human Development Research Unit, Universitat Rovira i Virgili, IISPV, Reus, Spain.
[14]
Neonatal Department, Children's Memorial Health Institute, Warsaw, Poland.
[15]
Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
[16]
Division of Biostatistics, School of Public Health, University of Minnesota, A460 Mayo Building, MMC 303, 420 Delaware St. SE, Minneapolis, MN, 55455, USA.
[17]
Glotech, Inc., Rockville, MD, USA.
[18]
Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA, 19104, USA.
[19]
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA.
[20]
Wendy Klag Center for Autism and Developmental Disabilities Johns Hopkins University, Baltimore, MD, USA.;Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
[21]
Sorbonne Université and INSERM, Epidemiology of Allergic and Respiratory Diseases Department, Pierre Louis Institute of Epidemiology and Public Health (IPLESP UMRS 1136), Saint-Antoine Medical School, Paris Cedex 12, France.;Department of Community Medicine and Public Health, SMBB Medical University, Larkana, Pakistan.
[22]
Sorbonne Université and INSERM, Epidemiology of Allergic and Respiratory Diseases Department, Pierre Louis Institute of Epidemiology and Public Health (IPLESP UMRS 1136), Saint-Antoine Medical School, Paris Cedex 12, France.
[23]
Institut Desbrest de Santé Publique (IDESP), INSERM and Montpellier University, Montpellier, France.
[24]
Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, CPO Piemonte, Italy.
[25]
Center for Environmental Sciences, University of Hasselt, 3590, Diepenbeek, Belgium.
[26]
Department of Social Medicine, School of Medicine, University of Crete, Heraklion, Greece.
[27]
Unit Health, Flemish Institute for Technological Research (VITO), Mol, Belgium.;Faculty of Sciences, Hasselt University, Diepenbeek, Belgium.;Department of Pharmacology and Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Limburg, The Netherlands.
[28]
Unit Health, Flemish Institute for Technological Research (VITO), Mol, Belgium.
[29]
Centre de Recherche du Centre Hospitalier de l'Universite de Sherbrooke, Sherbrooke, Canada.
[30]
Department of Medicine, Universite de Sherbrooke, Sherbrooke, Canada.
[31]
Department of Biochemistry and Functional Genomics, Universite de Sherbrooke, Sherbrooke, Canada.;Clinical Department of Laboratory Medicine, Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean - Hôpital de Chicoutimi, Chicoutimi, Canada.
[32]
The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.;Division of Respiratory Medicine and Allergology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
[33]
The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.;Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
[34]
Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK.
[35]
Department of Public Health, Aarhus University, Aarhus, Denmark.
[36]
Periconceptional Epidemiology, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
[37]
Life Course Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
[38]
Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Center for Genes, Environment and Health, National Jewish Health, Denver, CO, USA.
[39]
Institute for Global Health (ISGlobal), Barcelona, Spain.;Universitat Pompeu Fabra (UPF), Barcelona, Spain.;CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
[40]
Bradford Institute for Health Research, Bradford, UK.
[41]
Institute for Advanced Biosciences, University Grenoble-Alpes, INSERM, CNRS, Grenoble, France.
[42]
Institute for Global Health (ISGlobal), Barcelona, Spain.;Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.;Center for Molecular Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.;Children's Environmental Health and Disease Prevention Research Center at Dartmouth, Lebanon, NH, USA.
[43]
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA.
[44]
Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, USA.
[45]
Department of Environmental Immunology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
[46]
2530 Meridian Pkwy, Suite 200, Durham, NC 27713, USA.
[47]
Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway.
[48]
Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.;Section for Statistics and Data Science, Department of Mathematics, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway.
[49]
Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
[50]
Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.;Bioinformatics Research Center, North Carolina State University, Raleigh, NC, USA.
[51]
Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.;Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.
[52]
Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.;Department of Obstetrics and Gynaecology, Duke University Medical Center, Durham, NC, USA.
[53]
Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.
[54]
Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, 80804, Munich, Germany.
[55]
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
[56]
Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, USA.
[57]
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.;Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
[58]
Department of Obstetrics and Gynaecology, Duke University Medical Center, Durham, NC, USA.
[59]
Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, RTP, NC, 27709, USA.
[60]
Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.;David Hide Asthma and Allergy Research Centre, Isle of Wight, UK.;NIHR Southampton Biomedical Research Centre, Southampton General Hospital, Southampton, UK.
[61]
Department of Environmental Science, Vytautas Magnus University, 44248, Kaunas, Lithuania.
[62]
Life Course Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
[63]
Department of Clinical Research, Odense Universitetshospital, Odense, Denmark.
[64]
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.;Department Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
[65]
The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.;Division of Respiratory Medicine and Allergology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.;Division of Neonatology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
[66]
Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, USA.;Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
[67]
Provincial Institute for Hygiene, Antwerp, Belgium.
[68]
Institute for Global Health (ISGlobal), Barcelona, Spain.
[69]
Center for Environmental Sciences, University of Hasselt, 3590, Diepenbeek, Belgium.;Department of Public Health and Primary Care, Leuven University, Louvain, Belgium.
[70]
Epidemiology Branch, Division of Population Health Research, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6710B Rockledge Dr, MSC 7004, Bethesda, MD, USA.
[71]
Children's Environmental Health Laboratory, CERCH, Berkeley Public Health, University of California, 2121 Berkeley Way #5216, Berkeley, CA, 94720, USA.
[72]
Center for Genetic Epidemiology, University of Southern California, Los Angeles, CA, 90033, USA.;Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90033, USA.
[73]
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.;Sachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden.
[74]
Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;School of Psychology, University of Exeter, Exeter, UK.
[75]
Medical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia.;Medical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine, London, UK.
[76]
Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.;Department of Computer Science, Aberystwyth University, Aberystwyth, Ceredigion, UK.
[77]
Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK. J.W.Holloway@soton.ac.uk.;NIHR Southampton Biomedical Research Centre, Southampton General Hospital, Southampton, UK. J.W.Holloway@soton.ac.uk.
[78]
主题词
儿童(Child);儿童, 学龄前(Child, Preschool);人类(Humans);婴儿(Infant);婴儿, 新生(Infant, Newborn);哮喘(Asthma);DNA甲基化(DNA Methylation);炎症(Inflammation);季节(Seasons)
DOI
10.1186/s13148-023-01542-5
PMID
37697338
发布时间
2025-02-13
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Clinical epigenetics
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