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Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude.

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第一作者: Latha,Kadalayil
第一单位: Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.;Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.
作者: Latha,Kadalayil [1] ; Md Zahangir,Alam [2] ; Cory Haley,White [3] ; Akram,Ghantous [4] ; Esther,Walton [5] ; Olena,Gruzieva [6] ; Simon Kebede,Merid [7] ; Ashish,Kumar [8] ; Ritu P,Roy [9] ; Olivia,Solomon [10] ; Karen,Huen [10] ; Brenda,Eskenazi [10] ; Peter,Rzehak [11] ; Veit,Grote [11] ; Jean-Paul,Langhendries [12] ; Elvira,Verduci [13] ; Natalia,Ferre [14] ; Darek,Gruszfeld [15] ; Lu,Gao [16] ; Weihua,Guan [17] ; Xuehuo,Zeng [18] ; Enrique F,Schisterman [19] ; John F,Dou [20] ; Kelly M,Bakulski [20] ; Jason I,Feinberg [21] ; Munawar Hussain,Soomro [22] ; Giancarlo,Pesce [23] ; Nour,Baiz [24] ; Elena,Isaevska [25] ; Michelle,Plusquin [26] ; Marina,Vafeiadi [27] ; Theano,Roumeliotaki [27] ; Sabine A S,Langie [28] ; Arnout,Standaert [29] ; Catherine,Allard [30] ; Patrice,Perron [31] ; Luigi,Bouchard [32] ; Evelien R,van Meel [33] ; Janine F,Felix [34] ; Vincent W V,Jaddoe [34] ; Paul D,Yousefi [35] ; Cecilia H,Ramlau-Hansen [36] ; Caroline L,Relton [35] ; Elmar W,Tobi [37] ; Anne P,Starling [38] ; Ivana V,Yang [39] ; Maria,Llambrich [40] ; Gillian,Santorelli [41] ; Johanna,Lepeule [42] ; Lucas A,Salas [43] ; Mariona,Bustamante [40] ; Susan L,Ewart [44] ; Hongmei,Zhang [45] ; Wilfried,Karmaus [45] ; Stefan,Röder [46] ; Ana Claudia,Zenclussen [46] ; Jianping,Jin [47] ; Wenche,Nystad [48] ; Christian M,Page [49] ; Maria,Magnus [50] ; Dereje D,Jima [51] ; Cathrine,Hoyo [52] ; Rachel L,Maguire [53] ; Tuomas,Kvist [54] ; Darina,Czamara [55] ; Katri,Räikkönen [54] ; Tong,Gong [56] ; Vilhelmina,Ullemar [56] ; Sheryl L,Rifas-Shiman [57] ; Emily,Oken [57] ; Catarina,Almqvist [58] ; Robert,Karlsson [56] ; Jari,Lahti [54] ; Susan K,Murphy [59] ; Siri E,Håberg [50] ; Stephanie,London [60] ; Gunda,Herberth [46] ; Hasan,Arshad [61] ; Jordi,Sunyer [40] ; Regina,Grazuleviciene [62] ; Dana,Dabelea [63] ; Régine P M,Steegers-Theunissen [37] ; Ellen A,Nohr [64] ; Thorkild I A,Sørensen [65] ; Liesbeth,Duijts [66] ; Marie-France,Hivert [67] ; Vera,Nelen [68] ; Maja,Popovic [25] ; Manolis,Kogevinas [69] ; Tim S,Nawrot [70] ; Zdenko,Herceg [4] ; Isabella,Annesi-Maesano [24] ; M Daniele,Fallin [21] ; Edwina,Yeung [71] ; Carrie V,Breton [16] ; Berthold,Koletzko [11] ; Nina,Holland [72] ; Joseph L,Wiemels [73] ; Erik,Melén [74] ; Gemma C,Sharp [75] ; Matt J,Silver [76] ; Faisal I,Rezwan [77] ; John W,Holloway [78]
作者单位: Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.;Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK. [1] Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.;Department of Computer Science and Engineering, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh. [2] Merck Exploratory Science Center in Cambridge MA, Merck Research Laboratories, Cambridge, MA, 02141, USA. [3] Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France. [4] Department of Psychology, University of Bath, Bath, UK. [5] Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.;Centre for Occupational and Environmental Medicine, Region Stockholm, Sweden. [6] Centre for Occupational and Environmental Medicine, Region Stockholm, Sweden. [7] Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden. [8] Helen Diller Family Comprehensive Cancer Center University of California, San Francisco, CA, 94143, USA.;Computational Biology and Informatics Core, University of California, San Francisco, CA, 94143, USA. [9] Children's Environmental Health Laboratory, University of California, Berkeley, CA, USA. [10] Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany. [11] CHC, St Vincent, Liège-Rocourt, Belgium. [12] Department of Pediatrics, Vittore Buzzi Children Hospital, University of Milan, Milan, Italy. [13] Pediatric Nutrition and Human Development Research Unit, Universitat Rovira i Virgili, IISPV, Reus, Spain. [14] Neonatal Department, Children's Memorial Health Institute, Warsaw, Poland. [15] Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA. [16] Division of Biostatistics, School of Public Health, University of Minnesota, A460 Mayo Building, MMC 303, 420 Delaware St. SE, Minneapolis, MN, 55455, USA. [17] Glotech, Inc., Rockville, MD, USA. [18] Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA, 19104, USA. [19] Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA. [20] Wendy Klag Center for Autism and Developmental Disabilities Johns Hopkins University, Baltimore, MD, USA.;Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. [21] Sorbonne Université and INSERM, Epidemiology of Allergic and Respiratory Diseases Department, Pierre Louis Institute of Epidemiology and Public Health (IPLESP UMRS 1136), Saint-Antoine Medical School, Paris Cedex 12, France.;Department of Community Medicine and Public Health, SMBB Medical University, Larkana, Pakistan. [22] Sorbonne Université and INSERM, Epidemiology of Allergic and Respiratory Diseases Department, Pierre Louis Institute of Epidemiology and Public Health (IPLESP UMRS 1136), Saint-Antoine Medical School, Paris Cedex 12, France. [23] Institut Desbrest de Santé Publique (IDESP), INSERM and Montpellier University, Montpellier, France. [24] Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, CPO Piemonte, Italy. [25] Center for Environmental Sciences, University of Hasselt, 3590, Diepenbeek, Belgium. [26] Department of Social Medicine, School of Medicine, University of Crete, Heraklion, Greece. [27] Unit Health, Flemish Institute for Technological Research (VITO), Mol, Belgium.;Faculty of Sciences, Hasselt University, Diepenbeek, Belgium.;Department of Pharmacology and Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Limburg, The Netherlands. [28] Unit Health, Flemish Institute for Technological Research (VITO), Mol, Belgium. [29] Centre de Recherche du Centre Hospitalier de l'Universite de Sherbrooke, Sherbrooke, Canada. [30] Department of Medicine, Universite de Sherbrooke, Sherbrooke, Canada. [31] Department of Biochemistry and Functional Genomics, Universite de Sherbrooke, Sherbrooke, Canada.;Clinical Department of Laboratory Medicine, Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean - Hôpital de Chicoutimi, Chicoutimi, Canada. [32] The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.;Division of Respiratory Medicine and Allergology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. [33] The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.;Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. [34] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK. [35] Department of Public Health, Aarhus University, Aarhus, Denmark. [36] Periconceptional Epidemiology, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. [37] Life Course Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [38] Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Center for Genes, Environment and Health, National Jewish Health, Denver, CO, USA. [39] Institute for Global Health (ISGlobal), Barcelona, Spain.;Universitat Pompeu Fabra (UPF), Barcelona, Spain.;CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. [40] Bradford Institute for Health Research, Bradford, UK. [41] Institute for Advanced Biosciences, University Grenoble-Alpes, INSERM, CNRS, Grenoble, France. [42] Institute for Global Health (ISGlobal), Barcelona, Spain.;Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.;Center for Molecular Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.;Children's Environmental Health and Disease Prevention Research Center at Dartmouth, Lebanon, NH, USA. [43] Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA. [44] Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, USA. [45] Department of Environmental Immunology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany. [46] 2530 Meridian Pkwy, Suite 200, Durham, NC 27713, USA. [47] Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway. [48] Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.;Section for Statistics and Data Science, Department of Mathematics, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway. [49] Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway. [50] Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.;Bioinformatics Research Center, North Carolina State University, Raleigh, NC, USA. [51] Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.;Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA. [52] Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.;Department of Obstetrics and Gynaecology, Duke University Medical Center, Durham, NC, USA. [53] Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland. [54] Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, 80804, Munich, Germany. [55] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. [56] Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, USA. [57] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.;Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden. [58] Department of Obstetrics and Gynaecology, Duke University Medical Center, Durham, NC, USA. [59] Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, RTP, NC, 27709, USA. [60] Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.;David Hide Asthma and Allergy Research Centre, Isle of Wight, UK.;NIHR Southampton Biomedical Research Centre, Southampton General Hospital, Southampton, UK. [61] Department of Environmental Science, Vytautas Magnus University, 44248, Kaunas, Lithuania. [62] Life Course Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.;Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. [63] Department of Clinical Research, Odense Universitetshospital, Odense, Denmark. [64] Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.;Department Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [65] The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.;Division of Respiratory Medicine and Allergology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.;Division of Neonatology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. [66] Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, USA.;Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA. [67] Provincial Institute for Hygiene, Antwerp, Belgium. [68] Institute for Global Health (ISGlobal), Barcelona, Spain. [69] Center for Environmental Sciences, University of Hasselt, 3590, Diepenbeek, Belgium.;Department of Public Health and Primary Care, Leuven University, Louvain, Belgium. [70] Epidemiology Branch, Division of Population Health Research, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6710B Rockledge Dr, MSC 7004, Bethesda, MD, USA. [71] Children's Environmental Health Laboratory, CERCH, Berkeley Public Health, University of California, 2121 Berkeley Way #5216, Berkeley, CA, 94720, USA. [72] Center for Genetic Epidemiology, University of Southern California, Los Angeles, CA, 90033, USA.;Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90033, USA. [73] Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.;Sachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden. [74] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;School of Psychology, University of Exeter, Exeter, UK. [75] Medical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia.;Medical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine, London, UK. [76] Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.;Department of Computer Science, Aberystwyth University, Aberystwyth, Ceredigion, UK. [77] Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK. J.W.Holloway@soton.ac.uk.;NIHR Southampton Biomedical Research Centre, Southampton General Hospital, Southampton, UK. J.W.Holloway@soton.ac.uk. [78]
DOI 10.1186/s13148-023-01542-5
PMID 37697338
发布时间 2025-02-13
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