The N6-methyladenosine demethylase FTO is required for odontoblast differentiation in vitro and dentine formation in mice by promoting RUNX2 exon 5 inclusion through RBM4.
第一作者:
Mi,Xu
第一单位:
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
作者:
主题词
动物(Animals);人类(Humans);男(雄)性(Male);小鼠(Mice);细胞分化(Cell Differentiation);核心结合因子α1亚基(Core Binding Factor Alpha 1 Subunit);牙髓(Dental Pulp);牙本质(Dentin);外显子(Exons);小鼠, 近交C57BL(Mice, Inbred C57BL);成牙质细胞(Odontoblasts);RNA, 信使(RNA, Messenger);RNA结合蛋白质类(RNA-Binding Proteins);X线显微体层摄影术(X-Ray Microtomography)
DOI
10.1111/iej.13975
PMID
37698901
发布时间
2023-11-13
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International endodontic journal
1534-1549页
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