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A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection.

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第一作者： Jiawei,Pei

第一单位： key Lab for Space Biosciences and Biotechnology, School of Life Science, Northwestern Polytechnical University, Xi'an, Shaanxi, China.

作者： Jiawei,Pei ^[1] ; Ye,Tian ^[1] ; Wei,Ye ^[2] ; Jiangfan,Han ^[1] ; Yamei,Dang ^[2] ; Tong,Cheng ^[3] ; Wei,Wang ^[3] ; Yipu,Zhao ^[1] ; Weiliang,Ye ^[4] ; Shuyuan,Huangfu ^[1] ; Yu,Li ^[5] ; Fanglin,Zhang ^[6] ; Yingfeng,Lei ^[7] ; Airong,Qian ^[8]

作者单位： key Lab for Space Biosciences and Biotechnology, School of Life Science, Northwestern Polytechnical University, Xi'an, Shaanxi, China. ^[1] Department of Microbiology, School of Preclinical Medicine, Airforce Medical University: Fourth Military Medical University, Xi'an, Shaanxi, China. ^[2] State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, China. ^[3] Department of Pharmaceutics, School of Pharmacy, Fourth Military Medical University, Xi'an, Shaanxi, China. ^[4] Institute of Medical Research, Northwestern Polytechnical University, Xi'an, Shaanxi, China. liyu@nwpu.edu.cn. ^[5] Department of Microbiology, School of Preclinical Medicine, Airforce Medical University: Fourth Military Medical University, Xi'an, Shaanxi, China. flzhang@fmmu.edu.cn. ^[6] Department of Microbiology, School of Preclinical Medicine, Airforce Medical University: Fourth Military Medical University, Xi'an, Shaanxi, China. yflei@fmmu.edu.cn. ^[7] key Lab for Space Biosciences and Biotechnology, School of Life Science, Northwestern Polytechnical University, Xi'an, Shaanxi, China. qianair@nwpu.edu.cn. ^[8]

关键词 3D human epidermal skin model Flexible nano-liposomes Recombinant siRNA Varicella zoster virus (VZV)r/si-ORF7

DOI 10.1186/s13578-023-01108-1

PMID 37700336

发布时间 2023-11-20

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