首页> Journal of experimental & clinical cancer research : CR> Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation.

Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation.

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第一作者： Junhao,Zheng

第一单位： Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China.;Zhejiang Minimal Invasive Diagnosis and Treatment Technology Research Center of Severe Hepatobiliary Disease, Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment 310016, Hangzhou, China.;Zhejiang University Cancer Center, Hangzhou, 310058, China.;Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 311121, China.

作者： Junhao,Zheng ^[1] ; Yali,Wang ^[1] ; Liye,Tao ^[1] ; Jingwei,Cai ^[1] ; Zefeng,Shen ^[1] ; Yang,Liu ^[1] ; Haoyu,Pan ^[1] ; Shihao,Li ^[1] ; Yeling,Ruan ^[1] ; Tianyi,Chen ^[1] ; Zhengtao,Ye ^[1] ; Kainan,Lin ^[1] ; Yin,Sun ^[2] ; Junjie,Xu ^[3] ; Xiao,Liang ^[4]

作者单位： Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China.;Zhejiang Minimal Invasive Diagnosis and Treatment Technology Research Center of Severe Hepatobiliary Disease, Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment 310016, Hangzhou, China.;Zhejiang University Cancer Center, Hangzhou, 310058, China.;Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 311121, China. ^[1] Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY, 14642, USA. ^[2] Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China. walter235@zju.edu.cn.;Zhejiang Minimal Invasive Diagnosis and Treatment Technology Research Center of Severe Hepatobiliary Disease, Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment 310016, Hangzhou, China. walter235@zju.edu.cn.;Zhejiang University Cancer Center, Hangzhou, 310058, China. walter235@zju.edu.cn.;Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 311121, China. walter235@zju.edu.cn. ^[3] Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China. srrshlx@zju.edu.cn.;Zhejiang Minimal Invasive Diagnosis and Treatment Technology Research Center of Severe Hepatobiliary Disease, Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment 310016, Hangzhou, China. srrshlx@zju.edu.cn.;Zhejiang University Cancer Center, Hangzhou, 310058, China. srrshlx@zju.edu.cn.;Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 311121, China. srrshlx@zju.edu.cn. ^[4]

关键词 AKT Circ-RAPGEF5 Intrahepatic cholangiocarcinoma SAE1 SUMOylation