PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti-PD-1 Immunotherapy.

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第一作者： Yimin,Zheng

第一单位： Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Shanghai Key Laboratory of Organ Transplantation, Zhongshan Hospital, Shanghai, 200032, P. R. China.

作者： Yimin,Zheng ^[1] ; Yining,Wang ^[1] ; Zhou,Lu ^[1] ; Jinkai,Wan ^[2] ; Lulu,Jiang ^[3] ; Danjun,Song ^[4] ; Chuanyuan,Wei ^[1] ; Chao,Gao ^[1] ; Guoming,Shi ^[1] ; Jian,Zhou ^[1] ; Jia,Fan ^[1] ; Aiwu,Ke ^[1] ; Lu,Zhou ^[3] ; Jiabin,Cai ^[1]

作者单位： Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Shanghai Key Laboratory of Organ Transplantation, Zhongshan Hospital, Shanghai, 200032, P. R. China. ^[1] Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, P. R. China. ^[2] Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, P. R. China. ^[3] Department of Interventional Therapy, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, P. R. China. ^[4]

关键词 carcinogen metabolism ferroptosis hepatocellular carcinoma immunotherapy

主题词人类(Humans);癌, 肝细胞(Carcinoma, Hepatocellular);肝肿瘤(Liver Neoplasms);磷酸甘油酸酯变位酶(Phosphoglycerate Mutase);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);免疫疗法(Immunotherapy)

DOI 10.1002/advs.202301928

PMID 37705495

发布时间 2023-10-23

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2023年10卷29期

e2301928页

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PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti-PD-1 Immunotherapy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti-PD-1 Immunotherapy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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