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TFEB and TFE3 control glucose homeostasis by regulating insulin gene expression.

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第一作者： Adrien,Pasquier

第一单位： Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.

作者： Adrien,Pasquier ^[1] ; Nunzia,Pastore ^[2] ; Luca,D'Orsi ^[1] ; Rita,Colonna ^[1] ; Alessandra,Esposito ^[1] ; Veronica,Maffia ^[1] ; Rossella,De Cegli ^[1] ; Margherita,Mutarelli ^[3] ; Susanna,Ambrosio ^[1] ; Gennaro,Tufano ^[1] ; Antonio,Grimaldi ^[1] ; Marcella,Cesana ^[1] ; Davide,Cacchiarelli ^[4] ; Nathalie,Delalleau ^[5] ; Gennaro,Napolitano ^[4] ; Andrea,Ballabio ^[6]

作者单位： Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy. ^[1] Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.;Medical Genetics Unit, Department of Medical and Translational Science, Federico II University, Naples, Italy. ^[2] Institute of Applied Sciences and Intelligent Systems, National Research Council (ISASI-CNR), Pozzuoli, Italy. ^[3] Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.;Medical Genetics Unit, Department of Medical and Translational Science, Federico II University, Naples, Italy.;School for Advanced Studies, Genomics and Experimental Medicine Program, University of Naples "Federico II", Naples, Italy. ^[4] University of Lille, U1190-EGID, Lille, France.;Inserm, U1190, Lille, France. ^[5] Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy.;Medical Genetics Unit, Department of Medical and Translational Science, Federico II University, Naples, Italy.;School for Advanced Studies, Genomics and Experimental Medicine Program, University of Naples "Federico II", Naples, Italy.;Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.;Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA. ^[6]

关键词 TFEB beta cells glucose homeostasis insulin mTORC1