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Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury.

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第一作者： Wali,Muhammad

第一单位： MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310058, China.

作者： Wali,Muhammad ^[1] ; Yiru,Zhang ^[2] ; Jiaqi,Zhu ^[2] ; Jieqi,Xie ^[1] ; Shuqin,Wang ^[1] ; Ruo,Wang ^[2] ; Bing,Feng ^[2] ; Jiahang,Zhou ^[2] ; Wenyi,Chen ^[2] ; Yanping,Xu ^[2] ; Qigu,Yao ^[2] ; Yingduo,Yu ^[2] ; Hongcui,Cao ^[3] ; Changyou,Gao ^[4]

作者单位： MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310058, China. ^[1] State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou 310003, China. ^[2] State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou 310003, China. Electronic address: hccao@zju.edu.cn. ^[3] MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310058, China; Center for Healthcare Materials, Shaoxing Institute, Zhejiang University, Shaoxing 312099, China. Electronic address: cygao@zju.edu.cn. ^[4]

关键词 Acute lung injury Azithromycin Dual-drug Ibuprofen ROS-responsive NPs