Advanced glycation end products promote intervertebral disc degeneration by transactivation of matrix metallopeptidase genes.

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第一作者： Changchun,Tseng

第一单位： Department of Spine Surgery, Department of Orthopedics, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

作者： Changchun,Tseng ^[1] ; Bin,Chen ^[1] ; Yingchao,Han ^[1] ; Kun,Wang ^[1] ; Qingxin,Song ^[1] ; Hongxing,Shen ^[1] ; Zhi,Chen ^[2]

作者单位： Department of Spine Surgery, Department of Orthopedics, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. ^[1] Department of Spine Surgery, Department of Orthopedics, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. Electronic address: chenzhi@shmu.edu.cn. ^[2]

关键词 AP1 Advanced glycation end products IVD degeneration MMP PAK1 PPRC1

主题词人类(Humans);小鼠(Mice);动物(Animals);转录激活(Transcriptional Activation);小鼠, 近交C57BL(Mice, Inbred C57BL);金属蛋白酶类(Metalloproteases)

DOI 10.1016/j.joca.2023.09.005

PMID 37717904

发布时间 2024-02-06

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