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Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART.

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第一作者： Oscar,Blanch-Lombarte

第一单位： IrsiCaixa AIDS Research Institute, Barcelona, Spain.;Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Barcelona, Spain.

作者： Oscar,Blanch-Lombarte ^[1] ; Dan,Ouchi ^[2] ; Esther,Jimenez-Moyano ^[2] ; Julieta,Carabelli ^[2] ; Miguel Angel,Marin ^[2] ; Ruth,Peña ^[2] ; Adam,Pelletier ^[3] ; Aarthi,Talla ^[3] ; Ashish,Sharma ^[3] ; Judith,Dalmau ^[2] ; José Ramón,Santos ^[4] ; Rafick-Pierre,Sékaly ^[3] ; Bonaventura,Clotet ^[5] ; Julia G,Prado ^[6]

作者单位： IrsiCaixa AIDS Research Institute, Barcelona, Spain.;Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Barcelona, Spain. ^[1] IrsiCaixa AIDS Research Institute, Barcelona, Spain. ^[2] Pathology Department, Case Western Reserve University, Cleveland, United States. ^[3] Lluita contra la SIDA Foundation, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.;Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. ^[4] IrsiCaixa AIDS Research Institute, Barcelona, Spain.;Lluita contra la SIDA Foundation, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.;Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.;Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.;Faculty of Medicine, University of Vic - Central University of Catalonia (UVic-UCC), Catalonia, Spain. ^[5] IrsiCaixa AIDS Research Institute, Barcelona, Spain.;Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.;CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain. ^[6]

关键词 CD107a HIV-1-specific CD8+ T cells TIGIT immunology inflammation inhibitory receptors people living with HIV-1 single-cell CD8+ dynamics viruses

医学主题词人类(Humans);HIV-1(HIV-1);抗逆转录病毒药(Anti-Retroviral Agents);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);受体, 免疫(Receptors, Immunologic)

DOI 10.7554/eLife.83737

PMID 37723971

发布时间 2023-09-26

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准确一般字义偏差语意偏离译文作用小提交