Combination therapy with WEE1 inhibition and trifluridine/tipiracil against esophageal squamous cell carcinoma.

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第一作者： Trang H,Nguyen Vu

第一单位： Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.;Endoscopy Department, Cho Ray Hospital, Ho Chi Minh City, Vietnam.

作者： Trang H,Nguyen Vu ^[1] ; Osamu,Kikuchi ^[2] ; Shinya,Ohashi ^[3] ; Tomoki,Saito ^[4] ; Tomomi,Ida ^[4] ; Yukie,Nakai ^[4] ; Yang,Cao ^[4] ; Yoshihiro,Yamamoto ^[4] ; Yuki,Kondo ^[4] ; Yosuke,Mitani ^[4] ; Shigeki,Kataoka ^[4] ; Tomohiro,Kondo ^[4] ; Chikatoshi,Katada ^[4] ; Atsushi,Yamada ^[4] ; Junichi,Matsubara ^[4] ; Manabu,Muto ^[5]

作者单位： Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.;Endoscopy Department, Cho Ray Hospital, Ho Chi Minh City, Vietnam. ^[1] Department of Clinical Bio-Resource Center, Kyoto University Hospital, Kyoto, Japan.;Division of Clinical Pharmacology and Cancer Immunotherapy, Kyoto University Center for Cancer Immunotherapy and Immunobiology, Kyoto, Japan. ^[2] Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.;Preemptive Medicine and Lifestyle Disease Research Center, Kyoto University Hospital, Kyoto, Japan. ^[3] Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ^[4] Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.;Department of Clinical Bio-Resource Center, Kyoto University Hospital, Kyoto, Japan. ^[5]

关键词 DNA damage response WEE1 inhibitor esophageal squamous cell carcinoma synthetic lethality trifluridine