Exploring anti-acute kidney injury mechanism of Dahuang-Gancao decoction by network pharmacology and experimental validation.

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作者： Rui,Wang ^[1] ; Yi,An ^[2] ; Yifang,Xu ^[1] ; Chengyin,Li ^[1] ; Qiyuan,Wang ^[1] ; Yinshui,Zou ^[1] ; Guangzhi,Wang ^[3]

作者单位： Department of Oncology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430065, P.R. China. ^[1] Department of Endocrinology, Second Affiliated Hospital of Wuhan University of Science and Technology, Wuhan 430065, P.R. China. ^[2] Department of General Surgery, The Second Hospital of Dalian Medical University, Dalian 116023, P.R. China. ^[3]

关键词 Dahuang-Gancao decoction SIRT3/NRF2/HO-1 signaling pathway acute kidney injury experimental validation network pharmacology

主题词动物(Animals);小鼠(Mice);脂多糖类(Lipopolysaccharides);NF-E2相关因子2(NF-E2-Related Factor 2);抗衰老酶3(Sirtuin 3);急性肾损伤(Acute Kidney Injury)

DOI 10.18632/aging.205033

PMID 37724901

发布时间 2023-10-27

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准确一般字义偏差语意偏离译文作用小提交