Brahma-related gene 1 acts as a profibrotic mediator and targeting it by micheliolide ameliorates peritoneal fibrosis.

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作者： Shuting,Li ^[1] ; Congwei,Luo ^[1] ; Sijia,Chen ^[2] ; Yiyi,Zhuang ^[1] ; Yue,Ji ^[1] ; Yiqun,Zeng ^[1] ; Yao,Zeng ^[1] ; Xiaoyang,He ^[1] ; Jing,Xiao ^[1] ; Huizhen,Wang ^[1] ; Xiaowen,Chen ^[3] ; Haibo,Long ^[4] ; Fenfen,Peng ^[5]

作者单位： Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China. ^[1] Department of Nephrology and Rheumatology, The First Hospital of Changsha, Changsha, China. ^[2] Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China. 573281676@qq.com. ^[3] Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China. longhb1966@163.com. ^[4] Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China. doctorpff@163.com. ^[5]

关键词 BRG1 Micheliolide Peritoneal dialysis Peritoneal fibrosis TGF-β1

主题词动物(Animals);小鼠(Mice);疾病模型, 动物(Disease Models, Animal);腹膜透析(Peritoneal Dialysis);腹膜纤维化(Peritoneal Fibrosis);转化生长因子β1(Transforming Growth Factor beta1)

DOI 10.1186/s12967-023-04469-w

PMID 37726857

发布时间 2023-11-20

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