Implications of ubiquitination and the maintenance of replication fork stability in cancer therapy.

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作者： Donghui,Xia ^[1] ; Xuefei,Zhu ^[2] ; Ying,Wang ^[3] ; Peng,Gong ^[4] ; Hong-Shu,Su ^[3] ; Xingzhi,Xu ^[4]

作者单位： Shenzhen University General Hospital-Dehua Hospital Joint Research Center on Precision Medicine (sgh-dhhCPM), Dehua Hospital, Dehua, Quanzhou 362500, China. ^[1] Guangdong Key Laboratory for Genome Stability and Disease Prevention, Carson International Cancer Center, Marshall Laboratory of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518060, China. ^[2] State Key Laboratory of Agro-biotechnology and MOA Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing, China. ^[3] Department of General Surgery, Institute of Precision Diagnosis and Treatment of Gastrointestinal Tumors and Carson International Cancer Center, Shenzhen University General Hospital, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518060, China. ^[4]

关键词 cancer replication fork stability ubiquitination

主题词人类(Humans);DNA复制(DNA Replication);泛素化(Ubiquitination);DNA损伤(DNA Damage);基因组不稳定性(Genomic Instability);肿瘤(Neoplasms)

DOI 10.1042/BSR20222591

PMID 37728310

发布时间 2023-10-12

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