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BBB opening by low pulsed electric fields, depicted by delayed-contrast MRI, enables efficient delivery of therapeutic doxorubicin doses into mice brains.

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第一作者： Itzik,Cooper

第一单位： The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat-Gan, 52621, Israel. Itzik.Cooper@sheba.health.gov.il.;School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Itzik.Cooper@sheba.health.gov.il.;School of Psychology, Reichman University, Herzliya, Israel. Itzik.Cooper@sheba.health.gov.il.

作者： Itzik,Cooper ^[1] ; David,Last ^[2] ; Orly,Ravid ^[3] ; Daniel,Rand ^[3] ; Erez,Matsree ^[3] ; Liora,Omesi ^[3] ; Chen,Shemesh ^[3] ; Meir,Liberman ^[4] ; Leor,Zach ^[5] ; Orit,Furman ^[6] ; Dianne,Daniels ^[2] ; Sigal,Liraz-Zaltsman ^[7] ; Yael,Mardor ^[8] ; Shirley,Sharabi ^[9]

作者单位： The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat-Gan, 52621, Israel. Itzik.Cooper@sheba.health.gov.il.;School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Itzik.Cooper@sheba.health.gov.il.;School of Psychology, Reichman University, Herzliya, Israel. Itzik.Cooper@sheba.health.gov.il. ^[1] The Advanced Technology Center, Sheba Medical Center, Ramat-Gan, 52621, Israel. ^[2] The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat-Gan, 52621, Israel. ^[3] The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat-Gan, 52621, Israel.;School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. ^[4] School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.;Oncology Institute, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel. ^[5] Oncology Institute, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel. ^[6] The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat-Gan, 52621, Israel.;Department of Pharmacology, The Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.;Institute for Health and Medical Professions, Department of Sports Therapy, Ono Academic College, Kiryat Ono, Israel. ^[7] School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.;The Advanced Technology Center, Sheba Medical Center, Ramat-Gan, 52621, Israel. ^[8] The Advanced Technology Center, Sheba Medical Center, Ramat-Gan, 52621, Israel. Shirley.Sharabi@sheba.health.gov.il. ^[9]

关键词 Blood-brain barrier Brain tumor DCM Drug delivery MRI Pulsed electrical fields