首页> Acta pharmacologica Sinica> Rosmarinic acid in combination with ginsenoside Rg1 suppresses colon cancer metastasis via co-inhition of COX-2 and PD1/PD-L1 signaling axis.

Rosmarinic acid in combination with ginsenoside Rg1 suppresses colon cancer metastasis via co-inhition of COX-2 and PD1/PD-L1 signaling axis.

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第一作者： Huan,Liu

第一单位： Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.

作者： Huan,Liu ^[1] ; Rui,Deng ^[1] ; Cheng-Wei,Zhu ^[1] ; Hong-Kuan,Han ^[1] ; Gang-Fan,Zong ^[1] ; Lang,Ren ^[1] ; Peng,Cheng ^[1] ; Zhong-Hong,Wei ^[2] ; Yang,Zhao ^[3] ; Su-Yun,Yu ^[4] ; Yin,Lu ^[5]

作者单位： Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. ^[1] Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.;State Key Laboratory Cultivation Base for Traditional Chinese Medicine (TCM) Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. ^[2] School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. y.zhao@njucm.edu.cn. ^[3] School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. yusuyun@njucm.edu.cn. ^[4] Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. luyingreen@njucm.edu.cn.;State Key Laboratory Cultivation Base for Traditional Chinese Medicine (TCM) Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. luyingreen@njucm.edu.cn.;Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine (TCM) Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, 210023, China. luyingreen@njucm.edu.cn. ^[5]

关键词 COX-2 MYO10 PD-1/PD-L1 celecoxib colon cancer filopodia ginsenoside Rg1 metastasis rosmarinic acid