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ALDH1A3 promotes invasion and metastasis in triple-negative breast cancer by regulating the plasminogen activation pathway.

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第一作者： Alamelu G,Bharadwaj

第一单位： Department of Pathology, Dalhousie University, Halifax, Canada.

作者： Alamelu G,Bharadwaj ^[1] ; Meghan E,McLean ^[1] ; Margaret L,Dahn ^[1] ; Hannah F,Cahill ^[1] ; Marie-Claire D,Wasson ^[1] ; Raj Pranap,Arun ^[1] ; Olivia L,Walker ^[1] ; Brianne M,Cruickshank ^[2] ; Wasundara,Fernando ^[1] ; Jaganathan,Venkatesh ^[1] ; Penelope J,Barnes ^[1] ; Gillian,Bethune ^[1] ; Gregory,Knapp ^[2] ; Lucy K,Helyer ^[2] ; Carman A,Giacomantonio ^[3] ; David M,Waisman ^[4] ; Paola,Marcato ^[5]

作者单位： Department of Pathology, Dalhousie University, Halifax, Canada. ^[1] Department of Surgery, Dalhousie University, Halifax, Canada. ^[2] Department of Pathology, Dalhousie University, Halifax, Canada.;Department of Surgery, Dalhousie University, Halifax, Canada. ^[3] Department of Pathology, Dalhousie University, Halifax, Canada.;Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Canada. ^[4] Department of Pathology, Dalhousie University, Halifax, Canada.;Department of Microbiology and Immunology, Dalhousie University, Halifax, Canada.;Nova Scotia Health Authority, Halifax, Canada. ^[5]

关键词 ALDH1A3 invasion metastasis plasmin tPA triple-negative breast cancer

医学主题词人类(Humans);组织型纤溶酶原激活物(Tissue Plasminogen Activator);纤维蛋白溶酶(Fibrinolysin);醛脱氢酶(Aldehyde Dehydrogenase);尿激酶型纤溶酶原激活物(Urokinase-Type Plasminogen Activator);纤维蛋白溶酶原(Plasminogen);黑色素瘤(Melanoma)

DOI 10.1002/1878-0261.13528

PMID 37753740

发布时间 2024-01-06

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