Collective Synthesis of Sarpagine and Macroline Alkaloid-Inspired Compounds.

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第一作者： Hikaru,Aoyama

第一单位： Max Planck Institute of Molecular Physiology, Department of Chemical Biology, 44227, Dortmund, Germany.

作者： Hikaru,Aoyama ^[1] ; Caitlin,Davies ^[1] ; Jie,Liu ^[1] ; Axel,Pahl ^[1] ; Jan-Lukas,Kirchhoff ^[2] ; Rebecca,Scheel ^[3] ; Sonja,Sievers ^[3] ; Carsten,Strohmann ^[1] ; Michael,Grigalunas ^[2] ; Herbert,Waldmann ^[3]

作者单位： Max Planck Institute of Molecular Physiology, Department of Chemical Biology, 44227, Dortmund, Germany. ^[1] Compound Management and Screening Center, 44227, Dortmund, Germany. ^[2] Technical University Dortmund, Faculty of Chemistry, Inorganic Chemistry, 44227, Dortmund, Germany. ^[3] Technical University Dortmund, Faculty of Chemistry, Chemical Biology, 44227, Dortmund, Germany. ^[4]

关键词 biology-oriented synthesis divergent synthesis morphological profiling pseudo-natural products tubulin polymerization inhibitors

主题词微管蛋白(Tubulin);吲哚生物碱类(Indole Alkaloids);生物碱类(Alkaloids);抗肿瘤药(Antineoplastic Agents);生物制品(Biological Products)

DOI 10.1002/chem.202303027

PMID 37755456

发布时间 2024-01-24

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