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Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors.

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第一作者: Samantha E,Hoffman
第一单位: Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.;Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.;Harvard-MIT MD-PhD Program, Harvard Medical School, Boston, MA 02115, USA.;PhD Program in Biological and Biomedical Sciences, Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA.
作者单位: Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.;Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.;Harvard-MIT MD-PhD Program, Harvard Medical School, Boston, MA 02115, USA.;PhD Program in Biological and Biomedical Sciences, Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA. [1] Section of Hematology and Medical Oncology, Boston University School of Medicine and Boston Medical Center, Boston, MA 02118, USA.;Center for Regenerative Medicine, Boston University and Boston Medical Center, Boston, MA 02118, USA. [2] Center for Regenerative Medicine, Boston University and Boston Medical Center, Boston, MA 02118, USA. [3] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.;Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. [4] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.;Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.;PhD Program in Biological and Biomedical Sciences, Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA. [5] Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA. [6] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.;Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02115, USA.;Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. [7] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.;Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02115, USA. [8] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.;Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.;Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02115, USA. [9] Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. [10] Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. [11] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA. [12] Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. [13] Molecular Pathology Core Laboratory, Dana-Farber Cancer Institute, Boston, MA 02115, USA. [14] Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.;Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. [15] Section of Hematology and Medical Oncology, Boston University School of Medicine and Boston Medical Center, Boston, MA 02118, USA. [16]
DOI 10.1126/sciadv.add9668
PMID 37756410
发布时间 2024-09-26
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