Identification of neoepitope reactive T-cell receptors guided by HLA-A03:01 and HLA-A11:01 immunopeptidomics.

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第一作者： Catherine M,Ade

第一单位： Surgery Branch, National Cancer Institute, Bethesda, Maryland, USA catherine.ade@nih.gov.

作者： Catherine M,Ade ^[1] ; Matthew J,Sporn ^[2] ; Sudipto,Das ^[3] ; Zhiya,Yu ^[2] ; Ken-Ichi,Hanada ^[2] ; Yue A,Qi ^[4] ; Tapan,Maity ^[5] ; Xu,Zhang ^[6] ; Udayan,Guha ^[7] ; Thorkell,Andresson ^[3] ; James C,Yang ^[2]

作者单位： Surgery Branch, National Cancer Institute, Bethesda, Maryland, USA catherine.ade@nih.gov. ^[1] Surgery Branch, National Cancer Institute, Bethesda, Maryland, USA. ^[2] Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA. ^[3] Thoracic and GI Malignancies Branch, National Cancer Institute, Bethesda, Maryland, USA.;Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA. ^[4] Thoracic and GI Malignancies Branch, National Cancer Institute, Bethesda, Maryland, USA.;Laboratory of Cell Biology, National Cancer Institute, Bethesda, MD, USA. ^[5] Thoracic and GI Malignancies Branch, National Cancer Institute, Bethesda, Maryland, USA.;Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, USA. ^[6] Thoracic and GI Malignancies Branch, National Cancer Institute, Bethesda, Maryland, USA.;NextCure Inc, Beltsville, MD, USA. ^[7]

关键词 antigen presentation antigens immunotherapy immunotherapy, adoptive receptors, antigen

主题词人类(Humans);小鼠(Mice);动物(Animals);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));肿瘤(Neoplasms);抗原, 肿瘤(Antigens, Neoplasm);组织相容性抗原(Histocompatibility Antigens);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);肽类(Peptides);表位(Epitopes);肿瘤蛋白质类(Neoplasm Proteins);HLA-A抗原(HLA-A Antigens)

DOI 10.1136/jitc-2023-007097

PMID 37758652

发布时间 2023-10-04

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Journal for immunotherapy of cancer

2023年11卷9期

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Identification of neoepitope reactive T-cell receptors guided by HLA-A03:01 and HLA-A11:01 immunopeptidomics.

Journal for immunotherapy of cancer

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Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics.

Journal for immunotherapy of cancer

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Identification of neoepitope reactive T-cell receptors guided by HLA-A03:01 and HLA-A11:01 immunopeptidomics.