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Transcriptomics of Canine Inflammatory Mammary Cancer Treated with Empty Cowpea Mosaic Virus Implicates Neutrophils in Anti-Tumor Immunity.

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第一作者： Lucia,Barreno

第一单位： Department of Animal Medicine, Surgery and Pathology, Mammary Oncology Unit, Veterinary Teaching Hospital, Veterinary Medicine School, Complutense University of Madrid, 28040 Madrid, Spain.

作者： Lucia,Barreno ^[1] ; Natalia,Sevane ^[2] ; Guillermo,Valdivia ^[1] ; Daniel,Alonso-Miguel ^[1] ; María,Suarez-Redondo ^[1] ; Angela,Alonso-Diez ^[1] ; Steven,Fiering ^[3] ; Veronique,Beiss ^[4] ; Nicole F,Steinmetz ^[5] ; Maria Dolores,Perez-Alenza ^[1] ; Laura,Peña ^[1]

作者单位： Department of Animal Medicine, Surgery and Pathology, Mammary Oncology Unit, Veterinary Teaching Hospital, Veterinary Medicine School, Complutense University of Madrid, 28040 Madrid, Spain. ^[1] Department of Animal Production, Complutense University of Madrid, 28040 Madrid, Spain. ^[2] Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.;Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA. ^[3] Department of NanoEngineering, University of California San Diego, La Jolla, CA 92093, USA. ^[4] Department of NanoEngineering, University of California San Diego, La Jolla, CA 92093, USA.;Department of Radiology, University of California San Diego, 9500 Gilman Dr., La Jolla, CA 92093, USA.;Department of Bioengineering, University of California San Diego, 9500 Gilman Dr., La Jolla, CA 92093, USA.;Moores Cancer Center, University of California San Diego, 9500 Gilman Dr., La Jolla, CA 92093, USA.;Center for Nano-ImmunoEngineering, University of California San Diego, 9500 Gilman Dr., La Jolla, CA 92093, USA.;Institute for Materials Discovery and Design, University of California San Diego, 9500 Gilman Dr., La Jolla, CA 92093, USA.;Center for Engineering in Cancer, Institute for Engineering in Medicine, University of California San Diego, 9500 Gilman Dr., La Jolla, CA 92093, USA. ^[5]

关键词 canine mammary cancer model cowpea mosaic virus gene expression profile intratumor immunotherapy neutrophils tumor microenvironment