Group A Streptococcus Vaccine Targeting the Erythrogenic Toxins SpeA and SpeB Is Safe and Immunogenic in Rabbits and Does Not Induce Antibodies Associated with Autoimmunity.

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作者： Matthew J,Troese ^[1] ; Elodie,Burlet ^[1] ; Madeleine W,Cunningham ^[2] ; Kathy,Alvarez ^[2] ; Rebecca,Bentley ^[2] ; Nissy,Thomas ^[1] ; Shanna,Carwell ^[1] ; Garry L,Morefield ^[1]

作者单位： VaxForm, LLC., Bethlehem, PA 18015, USA. ^[1] Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. ^[2]

关键词 Group A Streptococcus (GAS)SpeA SpeB Streptococcus pyogenes Sydenham chorea (SC)autoantibodies pediatric autoimmune neuropsychiatric disorder associated with group A streptococci (PANDAS)rheumatic heart disease (RHD)safety vaccine

DOI 10.3390/vaccines11091504

PMID 37766180

发布时间 2024-06-15

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Vaccines

2023年11卷9期

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Group A Streptococcus Vaccine Targeting the Erythrogenic Toxins SpeA and SpeB Is Safe and Immunogenic in Rabbits and Does Not Induce Antibodies Associated with Autoimmunity.

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Group A Streptococcus Vaccine Targeting the Erythrogenic Toxins SpeA and SpeB Is Safe and Immunogenic in Rabbits and Does Not Induce Antibodies Associated with Autoimmunity.

Vaccines

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Vaccines

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