首页> Biochemistry. Biokhimiia> Novel B-Cell Epitopes of Non-Neutralizing Antibodies in the Receptor-Binding Domain of the SARS-CoV-2 S-Protein with Different Effects on the Severity of COVID-19.

Novel B-Cell Epitopes of Non-Neutralizing Antibodies in the Receptor-Binding Domain of the SARS-CoV-2 S-Protein with Different Effects on the Severity of COVID-19.

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第一作者： Andrey L,Matveev

第一单位： Federal State Public Scientific Institution "Institute of Chemical Biology and Fundamental Medicine", Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia. guterus@gmail.com.

作者： Andrey L,Matveev ^[1] ; Oleg V,Pyankov ^[2] ; Yana A,Khlusevich ^[3] ; Olga V,Tyazhelkova ^[3] ; Ljudmila A,Emelyanova ^[3] ; Anna M,Timofeeva ^[3] ; Andrey V,Shipovalov ^[2] ; Anton V,Chechushkov ^[3] ; Natalia S,Zaitseva ^[4] ; Gleb A,Kudrov ^[2] ; Gaukhar M,Yusubalieva ^[5] ; Saule M,Yussubaliyeva ^[6] ; Oxana A,Zhukova ^[7] ; Artem Yu,Tikunov ^[3] ; Vladimir P,Baklaushev ^[8] ; Sergey E,Sedykh ^[9] ; Galina I,Lifshits ^[3] ; Nina V,Tikunova ^[10]

作者单位： Federal State Public Scientific Institution "Institute of Chemical Biology and Fundamental Medicine", Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia. guterus@gmail.com. ^[1] State Research Center of Virology and Biotechnology "VECTOR", Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, 630559, Novosibirsk Region, Russia. ^[2] Federal State Public Scientific Institution "Institute of Chemical Biology and Fundamental Medicine", Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia. ^[3] FIC FTM, Novosibirsk, 630117, Russia. ^[4] Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, Moscow, 115682, Russia.;Federal Center of Brain Research and Neurotechnologies, FMBA of Russia, Moscow, 117513, Russia. ^[5] Astana Medical University, Nur-Sultan, 010000, Kazakhstan. ^[6] Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, Moscow, 115682, Russia. ^[7] Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, Moscow, 115682, Russia.;Pulmonology Research Institute FMBA of Russia, Moscow, 115682, Russia.;Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia. ^[8] Novosibirsk State University, Novosibirsk, 630090, Russia. ^[9] Federal State Public Scientific Institution "Institute of Chemical Biology and Fundamental Medicine", Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia.;Novosibirsk State University, Novosibirsk, 630090, Russia. ^[10]

关键词 COVID-19 RBD SARS-CoV-2 antibodies antiviral properties coronavirus infection receptor-binding domain

医学主题词动物(Animals);小鼠(Mice);人类(Humans);抗体, 中和(Antibodies, Neutralizing);表位, B淋巴细胞(Epitopes, B-Lymphocyte);抗体, 病毒(Antibodies, Viral)

DOI 10.1134/S000629792309002X

PMID 37770389

发布时间 2023-10-02

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