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Learning single-cell perturbation responses using neural optimal transport.

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第一作者： Charlotte,Bunne

第一单位： Department of Computer Science, ETH Zurich, Zürich, Switzerland.;AI Center, ETH Zurich, Zürich, Switzerland.

作者： Charlotte,Bunne ^[1] ; Stefan G,Stark ^[2] ; Gabriele,Gut ^[3] ; Jacobo Sarabia,Del Castillo ^[3] ; Mitch,Levesque ^[4] ; Kjong-Van,Lehmann ^[5] ; Lucas,Pelkmans ^[6] ; Andreas,Krause ^[7] ; Gunnar,Rätsch ^[8]

作者单位： Department of Computer Science, ETH Zurich, Zürich, Switzerland.;AI Center, ETH Zurich, Zürich, Switzerland. ^[1] Department of Computer Science, ETH Zurich, Zürich, Switzerland.;AI Center, ETH Zurich, Zürich, Switzerland.;Medical Informatics Unit, University of Zurich Hospital, Zürich, Switzerland.;Swiss Institute of Bioinformatics, Zurich, Switzerland. ^[2] Department of Molecular Life Sciences, University of Zurich, Zürich, Switzerland. ^[3] Department of Dermatology, University of Zurich Hospital, University of Zurich, Zürich, Switzerland. ^[4] Department of Computer Science, ETH Zurich, Zürich, Switzerland. kjlehmann@ukaachen.de.;Cancer Research Center Cologne-Essen, Site: Center Integrated Oncology Aachen, Aachen, Germany. kjlehmann@ukaachen.de. ^[5] Department of Molecular Life Sciences, University of Zurich, Zürich, Switzerland. lucas.pelkmans@mls.uzh.ch. ^[6] Department of Computer Science, ETH Zurich, Zürich, Switzerland. krausea@ethz.ch.;AI Center, ETH Zurich, Zürich, Switzerland. krausea@ethz.ch. ^[7] Department of Computer Science, ETH Zurich, Zürich, Switzerland. gunnar.raetsch@inf.ethz.ch.;AI Center, ETH Zurich, Zürich, Switzerland. gunnar.raetsch@inf.ethz.ch.;Medical Informatics Unit, University of Zurich Hospital, Zürich, Switzerland. gunnar.raetsch@inf.ethz.ch.;Swiss Institute of Bioinformatics, Zurich, Switzerland. gunnar.raetsch@inf.ethz.ch.;Department of Biology, ETH Zurich, Zürich, Switzerland. gunnar.raetsch@inf.ethz.ch. ^[8]

医学主题词人类(Humans);单细胞分析(Single-Cell Analysis);序列分析, RNA(Sequence Analysis, RNA);基因表达谱(Gene Expression Profiling)

DOI 10.1038/s41592-023-01969-x

PMID 37770709

发布时间 2025-12-03

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准确一般字义偏差语意偏离译文作用小提交