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Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion.

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第一作者: Xushen,Xiong
第一单位: Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA; Liangzhu Laboratory, Zhejiang University, 1369 West Wenyi Road, Hangzhou 311121, China.
作者单位: Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA; Liangzhu Laboratory, Zhejiang University, 1369 West Wenyi Road, Hangzhou 311121, China. [1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA. [2] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA; Department of Pathology and Laboratory Medicine, Department of Statistics, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. [3] Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA. [4] Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA. [5] Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. [6] Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612, USA. [7] The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: lhtsai@mit.edu. [8] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA. Electronic address: manoli@mit.edu. [9]
DOI 10.1016/j.cell.2023.08.040
PMID 37774680
发布时间 2024-11-14
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Cell

Cell

2023年186卷20期

4422-4437.e21页

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