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Engineering Clinically Relevant Probiotics with Switchable "Nano-Promoter" and "Nano-Effector" for Precision Tumor Therapy.

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作者: Fangfang,Cao [1] ; Lulu,Jin [2] ; Chenyin,Zhang [3] ; Yong,Gao [3] ; Zhefeng,Qian [3] ; Hongyang,Wen [3] ; Sisi,Yang [4] ; Ziqiang,Ye [3] ; Liangjie,Hong [4] ; Huang,Yang [5] ; Zongrui,Tong [3] ; Liang,Cheng [3] ; Yuan,Ding [3] ; Weilin,Wang [4] ; Guocan,Yu [6] ; Zhengwei,Mao [4] ; Xiaoyuan,Chen [4]
作者单位: Departments of Diagnostic Radiology Surgery Chemical and Biomolecular Engineering and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore. [1] Nanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore. [2] MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China. [3] Department of Hepatobiliary and Pancreatic Surgery, the Second Affiliated Hospital, School of Medicine Zhejiang University, Hangzhou, 310009, China. [4] State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine Zhejiang University, Hangzhou, 310003, China. [5] Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon Based Functional Materials & Devices, Soochow University, Suzhou, 215123, China. [6] Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China. [7] Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. [8] Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore. [9]
DOI 10.1002/adma.202304257
PMID 37788635
发布时间 2024-02-02
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Advanced materials (Deerfield Beach, Fla.)

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