MAGNETO: Cell type marker panel generator from single-cell transcriptomic data.

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作者： Andrea,Tangherloni ^[1] ; Simone G,Riva ^[2] ; Brynelle,Myers ^[3] ; Francesca M,Buffa ^[4] ; Paolo,Cazzaniga ^[5]

作者单位： Department of Computing Sciences, Bocconi University, Via Guglielmo Röntgen 1, Milan, 20136, Italy; Bocconi Institute for Data Science and Analytics, Bocconi University, Via Guglielmo Röntgen 1, Milan, 20136, Italy; Department of Human and Social Sciences, University of Bergamo, Piazzale S. Agostino 2, Bergamo, 24129, Italy. Electronic address: andrea.tangherloni@unibocconi.it. ^[1] Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Headley Way, Oxford, OX3 9DS, United Kingdom. ^[2] Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, United Kingdom. ^[3] Department of Computing Sciences, Bocconi University, Via Guglielmo Röntgen 1, Milan, 20136, Italy; Bocconi Institute for Data Science and Analytics, Bocconi University, Via Guglielmo Röntgen 1, Milan, 20136, Italy; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, United Kingdom. ^[4] Department of Human and Social Sciences, University of Bergamo, Piazzale S. Agostino 2, Bergamo, 24129, Italy; Bicocca Bioinformatics, Biostatistics, and Bioimaging Centre - B4, Via Follereau 3, Vedano al Lambro, 20854, Italy. ^[5]

关键词 Bioinformatics Marker gene selection Marker panels Multi-objective optimization Single-cell RNA-seq

主题词序列分析, RNA(Sequence Analysis, RNA);单细胞分析(Single-Cell Analysis);基因表达谱(Gene Expression Profiling);细胞分化(Cell Differentiation)

DOI 10.1016/j.jbi.2023.104510

PMID 37797704

发布时间 2023-11-14

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