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Universal features of Nsp1-mediated translational shutdown by coronaviruses.

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第一作者： Katharina,Schubert

第一单位： Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich 8049, Switzerland.

作者： Katharina,Schubert ^[1] ; Evangelos D,Karousis ^[2] ; Ivo,Ban ^[1] ; Christopher P,Lapointe ^[3] ; Marc,Leibundgut ^[1] ; Emilie,Bäumlin ^[4] ; Eric,Kummerant ^[1] ; Alain,Scaiola ^[1] ; Tanja,Schönhut ^[1] ; Jana,Ziegelmüller ^[5] ; Joseph D,Puglisi ^[3] ; Oliver,Mühlemann ^[5] ; Nenad,Ban ^[6]

作者单位： Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich 8049, Switzerland. ^[1] Department of Chemistry and Biochemistry, University of Bern, Bern 3012, Switzerland; Multidisciplinary Center for Infectious Diseases, University of Bern, Bern 3012, Switzerland. Electronic address: evangelos.karousis@unibe.ch. ^[2] Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. ^[3] Department of Chemistry and Biochemistry, University of Bern, Bern 3012, Switzerland; Multidisciplinary Center for Infectious Diseases, University of Bern, Bern 3012, Switzerland. ^[4] Department of Chemistry and Biochemistry, University of Bern, Bern 3012, Switzerland. ^[5] Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich 8049, Switzerland. Electronic address: ban@mol.biol.ethz.ch. ^[6]

关键词 Nsp1 SARS-CoV-2 cryoelectron microscopy ribosome translation

医学主题词动物(Animals);翼手目(Chiroptera);RNA, 信使(RNA, Messenger);病毒非结构蛋白质类(Viral Nonstructural Proteins)

DOI 10.1016/j.molcel.2023.09.002

PMID 37802027

发布时间 2024-10-06

基金项目

R01 GM113078/GM/NIGMS NIH HHS/United States R35 GM145306/GM/NIGMS NIH HHS/United States R00 GM144678/GM/NIGMS NIH HHS/United States K99 GM144678/GM/NIGMS NIH HHS/United States RF1 AG064690/AG/NIA NIH HHS/United States R01 AG064690/AG/NIA NIH HHS/United States

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