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Alzheimer's disease cortical morphological phenotypes are associated with TOMM40'523-APOE haplotypes.

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第一作者： Robyn A,Honea

第一单位： University of Kansas Alzheimer's Disease Center, University of Kansas School of Medicine, Kansas City, KS, USA; Department of Neurology, University of Kansas School of Medicine, Kansas City, KS, USA. Electronic address: rhonea@kumc.edu.

作者： Robyn A,Honea ^[1] ; Suzanne,Hunt ^[2] ; Rebecca J,Lepping ^[3] ; Eric D,Vidoni ^[4] ; Jill K,Morris ^[4] ; Amber,Watts ^[5] ; Elias,Michaelis ^[6] ; Jeffrey M,Burns ^[4] ; Russell H,Swerdlow ^[4]

作者单位： University of Kansas Alzheimer's Disease Center, University of Kansas School of Medicine, Kansas City, KS, USA; Department of Neurology, University of Kansas School of Medicine, Kansas City, KS, USA. Electronic address: rhonea@kumc.edu. ^[1] University of Kansas Alzheimer's Disease Center, University of Kansas School of Medicine, Kansas City, KS, USA. ^[2] University of Kansas Alzheimer's Disease Center, University of Kansas School of Medicine, Kansas City, KS, USA; Hoglund Biomedical Imaging Center, University of Kansas Medical Center, Kansas City, KS, USA; Department of Neurology, University of Kansas School of Medicine, Kansas City, KS, USA. ^[3] University of Kansas Alzheimer's Disease Center, University of Kansas School of Medicine, Kansas City, KS, USA; Department of Neurology, University of Kansas School of Medicine, Kansas City, KS, USA. ^[4] University of Kansas Alzheimer's Disease Center, University of Kansas School of Medicine, Kansas City, KS, USA; Department of Psychology, University of Kansas, Lawrence, KS, USA. ^[5] University of Kansas Alzheimer's Disease Center, University of Kansas School of Medicine, Kansas City, KS, USA; Department of Pharmacology and Toxicology, University of Kansas, Lawrence, KS, USA. ^[6]

关键词 APOE Alzheimer’s disease Cortical thickness Gray matter volume Mitochondria Neuroimage Poly-T TOMM40

医学主题词人类(Humans);单倍型(Haplotypes);阿尔茨海默病(Alzheimer Disease);载脂蛋白E4(Apolipoprotein E4);基因型(Genotype);表型(Phenotype)

DOI 10.1016/j.neurobiolaging.2023.09.001

PMID 37804609

发布时间 2025-03-07

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