Teriflunomide Promotes Blood-Brain Barrier Integrity by Upregulating Claudin-1 via the Wnt/β-catenin Signaling Pathway in Multiple Sclerosis.

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作者： Yipeng,Zhao ^[1] ; Chen,Chen ^[2] ; Xiuqing,Xiao ^[1] ; Ling,Fang ^[1] ; Xi,Cheng ^[3] ; Yanyu,Chang ^[4] ; Fuhua,Peng ^[1] ; Jingqi,Wang ^[1] ; Shishi,Shen ^[1] ; Shilin,Wu ^[1] ; Yiying,Huang ^[1] ; Wei,Cai ^[1] ; Linli,Zhou ^[1] ; Wei,Qiu ^[1]

作者单位： Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510000, China. ^[1] The Center of Mental and Neurological Disorders Study, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510000, China. ^[2] Shenzhen Key Laboratory of Cardiovascular Disease, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, 518057, China. ^[3] Department of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510000, China. ^[4] Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510000, China. qiuwei@mail.sysu.edu.cn. ^[5] The Center of Mental and Neurological Disorders Study, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510000, China. qiuwei@mail.sysu.edu.cn. ^[6]

关键词 Blood–brain barrier Claudin-1 Multiple sclerosis Teriflunomide Wnt signaling pathway