Novel Melanocortin-3 and -4 Receptor Functional Variants in Asian Children With Severe Obesity.

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作者： Siong Gim,Ong ^[1] ; Roghayeh,Dehghan ^[2] ; Rajkumar,Dorajoo ^[3] ; Jian-Jun,Liu ^[4] ; Andrew Anjian,Sng ^[3] ; Yung Seng,Lee ^[3] ; Delicia Shu Qin,Ooi ^[5]

作者单位： Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore. ^[1] Division of Paediatric Endocrinology, Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore 119228, Singapore. ^[2] Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore. ^[3] Department of Genetics and Molecular Biology, School of Medicine, University of Medical Science, Isfahan 81746-73461, Iran. ^[4] Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore. ^[5]

关键词 MC3R MC4R childhood obesity variants

主题词儿童(Child);人类(Humans);载体蛋白质类(Carrier Proteins);肥胖症, 病态(Obesity, Morbid);受体, 黑皮质素, 3型(Receptor, Melanocortin, Type 3);受体, 黑皮质素, 4型(Receptor, Melanocortin, Type 4)

DOI 10.1210/clinem/dgad602

PMID 37820740

发布时间 2024-07-01

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