Myeloid PTP1B deficiency protects against atherosclerosis by improving cholesterol homeostasis through an AMPK-dependent mechanism.

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第一作者： Helk,Oliver

第一单位： Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK. oliver.helk@meduniwien.ac.at.;Department of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. oliver.helk@meduniwien.ac.at.

作者： Helk,Oliver ^[1] ; Dekeryte,Ruta ^[2] ; Dawn,Thompson ^[2] ; Sarah,Kamli-Salino ^[2] ; Sam,Philip ^[3] ; Heather M,Wilson ^[2] ; Nimesh,Mody ^[2] ; Mirela,Delibegovic ^[4]

作者单位： Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK. oliver.helk@meduniwien.ac.at.;Department of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. oliver.helk@meduniwien.ac.at. ^[1] Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK. ^[2] Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.;Grampian Diabetes Research Unit, JJR Macleod Centre, NHS Grampian, Foresterhill, Aberdeen, AB25 2ZD, UK. ^[3] Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK. m.delibegovic@abdn.ac.uk. ^[4]

关键词 Atherosclerosis Cholesterol metabolism Myeloid cells PTP1B