首页> Cells> In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA.

In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA.

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第一作者： Marina,Reichlmeir

第一单位： Goethe University Frankfurt, University Hospital, Clinic of Neurology, Exp. Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany.

作者： Marina,Reichlmeir ^[1] ; Júlia,Canet-Pons ^[1] ; Gabriele,Koepf ^[1] ; Wasifa,Nurieva ^[2] ; Ruth Pia,Duecker ^[3] ; Claudia,Doering ^[4] ; Kathryn,Abell ^[5] ; Jana,Key ^[1] ; Matthew P,Stokes ^[5] ; Stefan,Zielen ^[6] ; Ralf,Schubert ^[3] ; Zoltán,Ivics ^[2] ; Georg,Auburger ^[1]

作者单位： Goethe University Frankfurt, University Hospital, Clinic of Neurology, Exp. Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany. ^[1] Transposition and Genome Engineering, Research Centre of the Division of Hematology, Gene and Cell Therapy, Paul Ehrlich Institute, 63225 Langen, Germany. ^[2] Division of Pediatrics, Pulmonology, Allergology, Infectious Diseases and Gastroenterology, Children's Hospital, University Hospital, Goethe-University, 60590 Frankfurt am Main, Germany. ^[3] Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany. ^[4] Cell Signaling Technology, Inc., Danvers, MA 01923, USA. ^[5] Division of Pediatrics, Pulmonology, Allergology, Infectious Diseases and Gastroenterology, Children's Hospital, University Hospital, Goethe-University, 60590 Frankfurt am Main, Germany.;Respiratory Research Institute, Medaimun GmbH, 60596 Frankfurt am Main, Germany. ^[6]

关键词 cerebellar ataxia cytoplasmic ATM synaptic pathology