Hepatocyte growth factor pretreatment boosts functional recovery after spinal cord injury through human iPSC-derived neural stem/progenitor cell transplantation.

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第一作者： Yu,Suematsu

第一单位： Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan.

作者： Yu,Suematsu ^[1] ; Narihito,Nagoshi ^[2] ; Munehisa,Shinozaki ^[3] ; Yoshitaka,Kase ^[2] ; Yusuke,Saijo ^[2] ; Shogo,Hashimoto ^[4] ; Takahiro,Shibata ^[1] ; Keita,Kajikawa ^[2] ; Yasuhiro,Kamata ^[1] ; Masahiro,Ozaki ^[1] ; Kaori,Yasutake ^[1] ; Tomoko,Shindo ^[1] ; Shinsuke,Shibata ^[1] ; Morio,Matsumoto ^[1] ; Masaya,Nakamura ^[5] ; Hideyuki,Okano ^[5]

作者单位： Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan. ^[1] Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan. ^[2] Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan. nagoshi@2002.jukuin.keio.ac.jp. ^[3] Department of Clinical Regenerative Medicine, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutukake-Cho, Toyoake-Shi, Aichi, 470-1192, Japan. ^[4] Electron Microscope Laboratory, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan. ^[5] Division of Microscopic Anatomy, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-Dori, Chuo-Ku, Niigata, Niigata, 951-8510, Japan. ^[6] Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan. hidokano@keio.jp. ^[7]

关键词 Cell transplantation therapy Combination therapy Hepatocyte growth factor Neural stem cells Neuroregeneration Spinal cord injury iPS cells

DOI 10.1186/s41232-023-00298-y

PMID 37845736

发布时间 2023-11-23

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