Astaxanthin protects against pirarubicin-induced H9c2 cardiomyocytes by adjusting microRNA-494-3p-mediated MDM4/p53 signalling pathway.

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第一作者： Peng,Huang

第一单位： Department of Experimental Pharmacology and Toxicology, School of Pharmacy, Jilin University, Changchun, China.

作者： Peng,Huang ^[1] ; Yibing,Zhang ^[2] ; Fengjun,Wang ^[3] ; Meng,Qin ^[1] ; Jiulong,Ma ^[1] ; Jiahua,Ji ^[1] ; Dexian,Wei ^[1] ; Liqun,Ren ^[1]

作者单位： Department of Experimental Pharmacology and Toxicology, School of Pharmacy, Jilin University, Changchun, China. ^[1] Department of Ophthalmology, The First Hospital of Jilin University, Changchun, China. ^[2] Department of Hepatobiliary Surgery, Songyuan Central Hospital, Songyuan, China. ^[3]

关键词 H9c2 astaxanthin miR-494-3p miR-494-3p/MDM4/p53 pirubicin

主题词大鼠(Rats);动物(Animals);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);细胞系(Cell Line);微RNAs(MicroRNAs);肌细胞, 心脏(Myocytes, Cardiac);细胞凋亡(Apoptosis)

DOI 10.1093/jpp/rgad084

PMID 37846109

发布时间 2023-12-16

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