High-plex spatial transcriptomic profiling reveals distinct immune components and the HLA class I/DNMT3A/CD8 modulatory axis in mismatch repair-deficient endometrial cancer.
作者:
主题词
人类(Humans);女(雌)性(Female);子宫内膜肿瘤(Endometrial Neoplasms);DNA错配修复(DNA Mismatch Repair);基因表达谱(Gene Expression Profiling);肿瘤微环境(Tumor Microenvironment);组织相容性抗原Ⅰ类(Histocompatibility Antigens Class I);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);中年人(Middle Aged);微卫星不稳定性(Microsatellite Instability);老年人(Aged)
DOI
10.1007/s13402-023-00885-8
PMID
37847338
发布时间
2024-06-11
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Cellular oncology (Dordrecht)
573-585页
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