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A multi-cohort phase 1b trial of rituximab in combination with immunotherapy doublets in relapsed/refractory follicular lymphoma.

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第一作者： Reid W,Merryman

第一单位： Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, USA. Reid_merryman@dfci.harvard.edu.

作者： Reid W,Merryman ^[1] ; Robert A,Redd ^[2] ; Arnold S,Freedman ^[3] ; Inhye E,Ahn ^[3] ; Jennifer R,Brown ^[3] ; Jennifer L,Crombie ^[3] ; Matthew S,Davids ^[3] ; David C,Fisher ^[3] ; Eric D,Jacobsen ^[3] ; Austin I,Kim ^[3] ; Ann S,LaCasce ^[3] ; Samuel,Ng ^[3] ; Oreofe O,Odejide ^[3] ; Erin M,Parry ^[3] ; Iris,Isufi ^[4] ; Justin,Kline ^[5] ; Jonathon B,Cohen ^[6] ; Neha,Mehta-Shah ^[7] ; Nancy L,Bartlett ^[7] ; Matthew,Mei ^[8] ; Thomas M,Kuntz ^[9] ; Jacquelyn,Wolff ^[10] ; Scott J,Rodig ^[11] ; Philippe,Armand ^[3] ; Caron A,Jacobson ^[3]

作者单位： Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, USA. Reid_merryman@dfci.harvard.edu. ^[1] Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA. ^[2] Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, USA. ^[3] Hematology, Yale University School of Medicine, New Haven, CT, USA. ^[4] Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL, USA. ^[5] Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA. ^[6] Department of Medicine, Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO, USA. ^[7] Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Medical Center, Duarte, CA, USA. ^[8] Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. ^[9] Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. ^[10] Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA. ^[11]

关键词 Follicular lymphoma Immune checkpoint Immunotherapy Rituximab Stool microbiome Tumor microenvironment