Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
第一作者:
Chinnaswamy,Tiruppathi
第一单位:
Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA. tiruc@uic.edu.
作者:
医学主题词
动物(Animals);小鼠(Mice);黏着连接(Adherens Junctions);泛素(Ubiquitin);连接酶类(Ligases);脂多糖类(Lipopolysaccharides);钙黏着糖蛋白类(Cadherins);内皮(Endothelium);泛素化(Ubiquitination);内皮, 血管(Endothelium, Vascular);细胞, 培养的(Cells, Cultured)
DOI
10.1038/s41467-023-42225-2
PMID
37852964
发布时间
2024-02-10
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