Identification of Cell Type-Specific Effects of <i>DNMT3A</i> Mutations on Relapse in Acute Myeloid Leukemia.

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第一作者： Seo-Gyeong,Bae

第一单位： School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea.

作者： Seo-Gyeong,Bae ^[1] ; Hyeoung-Joon,Kim ^[2] ; Mi Yeon,Kim ^[3] ; Dennis Dong Hwan,Kim ^[4] ; So-I,Shin ^[1] ; Jae-Sook,Ahn ^[2] ; Jihwan,Park ^[1]

作者单位： School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea. ^[1] Department of Internal Medicine, Chonnam National University Hwasun Hospital, Chonnam National University, Hwasun 58128, Korea.;Genomic Research Center for Hematopoietic Diseases, Chonnam National University Hwasun Hospital, Hwasun 58128, Korea. ^[2] Department of Internal Medicine, Chonnam National University Hwasun Hospital, Chonnam National University, Hwasun 58128, Korea. ^[3] Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON M5S 1A1, Canada. ^[4]

关键词 DNMT3A R882 acute myeloid leukemia cancer genomics copy number variation relapse single-cell RNA sequencing

主题词人类(Humans);DNA拷贝数变异(DNA Copy Number Variations);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);突变(Mutation);复发(Recurrence)

DOI 10.14348/molcells.2023.0093

PMID 37853686

发布时间 2024-02-04

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