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Surfaceome analysis of extracellular vesicles from senescent cells uncovers uptake repressor DPP4.

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第一作者： Qiong,Meng

第一单位： Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, NIH, Baltimore, MD 21224.

作者： Qiong,Meng ^[1] ; Chen,Chen ^[2] ; Na,Yang ^[1] ; Olesia,Gololobova ^[3] ; Changyou,Shi ^[1] ; Christopher A,Dunn ^[4] ; Martina,Rossi ^[1] ; Jennifer L,Martindale ^[1] ; Nathan,Basisty ^[5] ; Jun,Ding ^[5] ; Michael,Delannoy ^[6] ; Srikanta,Basu ^[7] ; Krystyna,Mazan-Mamczarz ^[1] ; Chang Hoon,Shin ^[1] ; Jen-Hao,Yang ^[1] ; Peter F,Johnson ^[7] ; Kenneth W,Witwer ^[3] ; Arya,Biragyn ^[2] ; Payel,Sen ^[1] ; Kotb,Abdelmohsen ^[1] ; Supriyo,De ^[1] ; Myriam,Gorospe ^[1]

作者单位： Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, NIH, Baltimore, MD 21224. ^[1] Laboratory of Molecular Biology and Immunology, National Institute on Aging Intramural Research Program, NIH, Baltimore, MD 21224. ^[2] Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205. ^[3] Flow Cytometry Unit, National Institute on Aging Intramural Research Program, NIH, Baltimore, MD 21224. ^[4] Translational Gerontology Branch, National Institute on Aging Intramural Research Program, NIH, Baltimore, MD 21224. ^[5] Department of Cell Biology and Imaging Facility, Johns Hopkins University School of Medicine, Baltimore, MD 21205. ^[6] Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702. ^[7]

关键词 extracellular vesicles senescence surfaceome

医学主题词人类(Humans);二肽基肽酶4(Dipeptidyl Peptidase 4);衰老(Aging)

DOI 10.1073/pnas.2219801120

PMID 37862381

发布时间 2025-09-29

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