Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease.

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第一作者： Mandy M,Chan

第一单位： Diabetes Research Center, Washington University School of Medicine, St. Louis, MO, USA.;Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.;Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

作者： Mandy M,Chan ^[1] ; Sabine,Daemen ^[2] ; Joseph W,Beals ^[3] ; Marina,Terekhova ^[4] ; Bin Q,Yang ^[5] ; Christina F,Fu ^[1] ; Li,He ^[6] ; Arick C,Park ^[7] ; Gordon I,Smith ^[3] ; Babak,Razani ^[8] ; Kathleen,Byrnes ^[4] ; Wandy L,Beatty ^[9] ; Shaina R,Eckhouse ^[10] ; J Christopher,Eagon ^[10] ; Daniel,Ferguson ^[3] ; Brian N,Finck ^[3] ; Samuel,Klein ^[3] ; Maxim N,Artyomov ^[4] ; Joel D,Schilling ^[1]

作者单位： Diabetes Research Center, Washington University School of Medicine, St. Louis, MO, USA.;Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.;Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. ^[1] Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands. ^[2] Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA. ^[3] Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. ^[4] Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. ^[5] Diabetes Research Center, Washington University School of Medicine, St. Louis, MO, USA.;Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. ^[6] Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. ^[7] Vascular Medicine Institute, Department of Medicine, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, PA, USA.;Division of Cardiology, Pittsburgh VA Medical Center, Pittsburgh, PA, USA. ^[8] Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA. ^[9] Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA. ^[10]

关键词 Inflammation Kupffer cells Liver steatosis Obesity

DOI 10.1016/j.jhepr.2023.100877

PMID 37869071

发布时间 2025-02-22

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JHEP reports

2023年5卷11期

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Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease.

JHEP reports

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Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease.

JHEP reports

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JHEP reports

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