Interspecies transcriptomic comparison identifies a potential porto-sinusoidal vascular disorder rat model suitable for in vivo drug testing.

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作者： Genís,Campreciós ^[1] ; Marina,Vilaseca ^[2] ; Dinesh M,Tripathi ^[3] ; Carla,Montironi ^[4] ; Alba,Díaz ^[5] ; Daniel,Aguilar ^[6] ; Héctor,García-Calderó ^[1] ; Rosa,Montañés ^[2] ; Aina,Anton ^[1] ; Virginia,Hernández-Gea ^[7] ; Joan Carles,García-Pagán ^[7]

作者单位： Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver), Barcelona, Catalonia, Spain.;Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain.;Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain. ^[1] Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver), Barcelona, Catalonia, Spain.;Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain. ^[2] Liver Physiology & Vascular Biology Group, Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences (ILBS), Vasant Kunj, New Delhi, India. ^[3] Pathology Department & Molecular Biology Core, Centre de Diagnòstic Biomèdic (CDB), Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Catalonia, Spain. ^[4] Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain.;Pathology Department, Biomedical Diagnostic Centre, Hospital Clínic Barcelona, Barcelona, Catalonia, Spain. ^[5] Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain. ^[6] Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver), Barcelona, Catalonia, Spain.;Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain.;Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain.;Medicine Department, Faculty of Medicine, University of Barcelona, Barcelona, Catalonia, Spain. ^[7]

关键词 animal model interspecies comparison porto-sinusoidal vascular disease (PSVD)