换一批
换一批GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.
作者：
Nick,Dand [1]
;
Philip E,Stuart [2]
;
John,Bowes [3]
;
David,Ellinghaus [4]
;
Joanne,Nititham [5]
;
Jake R,Saklatvala [6]
;
Maris,Teder-Laving [7]
;
Laurent F,Thomas [1]
;
Tanel,Traks [8]
;
Steffen,Uebe [9]
;
Gunter,Assmann [10]
;
David,Baudry [11]
;
Frank,Behrens [12]
;
Allison C,Billi [13]
;
Matthew A,Brown [14]
;
Harald,Burkhardt [15]
;
Francesca,Capon [16]
;
Raymond,Chung [17]
;
Charles J,Curtis [18]
;
Michael,Duckworth [19]
;
Eva,Ellinghaus [20]
;
Oliver,FitzGerald [21]
;
Sascha,Gerdes [3]
;
Christopher E M,Griffiths [1]
;
Susanne,Gulliver [22]
;
Philip,Helliwell [21]
;
Pauline,Ho [19]
;
Per,Hoffmann [20]
;
Oddgeir L,Holmen [1]
;
Zhi-Ming,Huang [23]
;
Kristian,Hveem [24]
;
Deepak,Jadon [23]
;
Michaela,Köhm [24]
;
Cornelia,Kraus [17]
;
Céline,Lamacchia [6]
;
Sang Hyuck,Lee [25]
;
Feiyang,Ma [26]
;
Satveer K,Mahil [27]
;
Neil,McHugh [17]
;
Ross,McManus [28]
;
Ellen H,Modalsli [29]
;
Michael J,Nissen [30]
;
Markus,Nöthen [31]
;
Vinzenz,Oji [4]
;
Jorge R,Oksenberg [5]
;
Matthew T,Patrick [32]
;
Bethany E,Perez-White [33]
;
Andreas,Ramming [34]
;
Jürgen,Rech [35]
;
Cheryl,Rosen [7]
;
Mrinal K,Sarkar [10]
;
Georg,Schett [34]
;
Börge,Schmidt [35]
;
Trilokraj,Tejasvi [36]
;
Heiko,Traupe [18]
;
John J,Voorhees [19]
;
Eike Matthias,Wacker [20]
;
Richard B,Warren [21]
;
Rachael,Wasikowski [14]
;
Stephan,Weidinger [37]
;
Xiaoquan,Wen [23]
;
Zhaolin,Zhang [24]
;
BSTOP study group [3]
;
Estonian Biobank research team [38]
;
Anne,Barton [17]
;
Vinod,Chandran [39]
;
Tõnu,Esko [40]
;
John,Foerster [41]
;
Andre,Franke [9]
;
Dafna D,Gladman [42]
;
Johann E,Gudjonsson [37]
;
Wayne,Gulliver [33]
;
Ulrike,Hüffmeier [43]
;
Külli,Kingo [44]
;
Sulev,Kõks [3]
;
Wilson,Liao [45]
;
Mari,Løset [46]
;
Reedik,Mägi [47]
;
Rajan P,Nair [46]
;
Proton,Rahman [47]
;
André,Reis [48]
;
Catherine H,Smith [3]
;
Paola,Di Meglio [46]
;
Jonathan N,Barker [47]
;
Lam C,Tsoi [49]
;
Michael A,Simpson [3]
;
James T,Elder [50]
作者单位：
Department of Medical & Molecular Genetics, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
[1]
Health Data Research UK, London, UK.
[2]
Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
[3]
Centre for Genetics and Genomics Versus Arthritis, The University of Manchester, Manchester, UK.
[4]
National Institute for Health and Care Research (NIHR) Manchester Biomedical Research Centre, The University of Manchester, Manchester, UK.
[5]
Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
[6]
Deparment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
[7]
Institute of Genomics, University of Tartu, Tartu, Estonia.
[8]
Department of Clinical and Molecular Medicine, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.
[9]
K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.
[10]
BioCore - Bioinformatics Core Facility, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.
[11]
Clinic of Laboratory Medicine, St.Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
[12]
Department of Dermatology and Venereology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
[13]
Institute of Human Genetics, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany.
[14]
RUB University Hospital JWK Minden, Department of Rheumatology, Minden, Germany.
[15]
Jose-Carreras Centrum for Immuno- and Gene Therapy, University of Saarland Medical School, Homburg, Germany.
[16]
St John's Institute of Dermatology, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
[17]
Division of Translational Rheumatology, Immunology - Inflammation Medicine, University Hospital, Goethe University, Frankfurt am Main, Germany.
[18]
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.
[19]
Fraunhofer Cluster of Excellence Immune-mediated Diseases CIMD, Frankfurt am Main, Germany.
[20]
Division of Rheumatology, University Hospital, Goethe University, Frankfurt am Main, Germany.
[21]
Genomics England, Canary Wharf, London, UK.
[22]
Institute of Psychiatry, Psychology and Neuroscience, King's College London, Denmark Hill, Camberwell, London, UK.
[23]
National Institute for Health and Care Research (NIHR) Biomedical Research Centre, South London and Maudsley Hospital, London, UK.
[24]
UCD School of Medicine and Medical Sciences and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland.
[25]
Department of Dermatology, Venereology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
[26]
Centre for Dermatology Research, University of Manchester, NIHR Manchester Biomedical Research Centre, Manchester, UK.
[27]
Department of Dermatology, King's College Hospital NHS Foundation Trust, London, UK.
[28]
Newlab Clinical Research Inc, St. John's, NL, Canada.
[29]
National Institute for Health and Care Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, UK.
[30]
Leeds Institute of Rheumatic and Musculoskeletal Disease, University of Leeds, UK.
[31]
The Kellgren Centre for Rheumatology, Manchester University NHS Foundation Trust, Manchester, UK.
[32]
Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.
[33]
HUNT Research Centre, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Levanger, Norway.
[34]
Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.
[35]
Department of Medicine, University of Cambridge, Cambridge, UK.
[36]
Division of Rheumatology, Geneva University Hospital, Geneva, Switzerland.
[37]
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
[38]
St John's Institute of Dermatology, Guy's and St Thomas' National Health Service (NHS) Foundation Trust, London, UK.
[39]
Royal National Hospital for Rheumatic Diseases and Dept Pharmacy and Pharmacology, University of Bath, UK.
[40]
Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Ireland.
[41]
Department of Dermatology, Clinic of Orthopedy, Rheumatology and Dermatology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
[42]
Department of Dermatology, University of Münster, Münster, Germany.
[43]
Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA.
[44]
Department of Dermatology, Northwestern University, Evanston, IL, USA.
[45]
Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany.
[46]
Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
[47]
Division of Dermatology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
[48]
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
[49]
Ann Arbor Veterans Affairs Hospital, Ann Arbor, MI, USA.
[50]
Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, UK.
[51]
Centre for Dermatology Research, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M6 8HD, UK.
[52]
Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
[53]
Schroeder Arthritis Institute, Krembil Research Institute, and Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.
[54]
College of Medicine, Dentistry, and Nursing, University of Dundee, Dundee, UK.
[55]
Department of Dermatology, Discipline of Medicine, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.
[56]
Dermatology Clinic, Tartu University Hospital, Tartu, Estonia.
[57]
Perron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.
[58]
Centre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University, Perth, WA 6150, Australia.
[59]
Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
[60]
Memorial University of Newfoundland, St. John's, NL, Canada.
[61]
DOI
10.1101/2023.10.04.23296543
PMID
37873414
发布时间
2024-03-20
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medRxiv
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