Delivery of Plasmid DNA by Ionizable Lipid Nanoparticles to Induce CAR Expression in T Cells.

导出 OA

翻译打印收藏纠错

第一作者： Pedro Henrique Dias Moura,Prazeres

第一单位： Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.;Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.

作者： Pedro Henrique Dias Moura,Prazeres ^[1] ; Heloísa,Ferreira ^[2] ; Pedro Augusto Carvalho,Costa ^[2] ; Walison,da Silva ^[2] ; Marco Túllio,Alves ^[2] ; Marshall,Padilla ^[3] ; Ajay,Thatte ^[3] ; Anderson Kenedy,Santos ^[4] ; Anderson Oliveira,Lobo ^[5] ; Adriano,Sabino ^[6] ; Helen Lima,Del Puerto ^[7] ; Michael J,Mitchell ^[3] ; Pedro Pires Goulart,Guimaraes ^[1]

作者单位： Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.;Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. ^[1] Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. ^[2] Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA. ^[3] Department of Pediatrics/Gastroenterology and Hepatology, Yale School of Medicine, New Haven, CT, USA.;Department of Genetics, Yale School of Medicine, New Haven, CT, USA. ^[4] Department of Materials Engineering, Federal University of Piauí, Teresina, PI, Brazil. ^[5] Department of Clinical and Toxicological Analysis, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. ^[6] Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. ^[7]

关键词 CAR T cells cancer immunotherapy cell engineering lipid nanoparticles pDNA delivery

主题词人类(Humans);辅药(Excipients);白细胞, 单核(Leukocytes, Mononuclear);质粒(Plasmids);纳米粒子(Nanoparticles);DNA(DNA);脂类(Lipids)

DOI 10.2147/IJN.S424723

PMID 37873551

发布时间 2023-10-27

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交