首页> Cell reports> Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion.

Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion.

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第一作者： Nishant Ranjan,Chauhan

第一单位： Cell Biology and Infectious Diseases Unit, Department of Infectious Disease Biology, Institute of Life Sciences, Bhubaneswar 751023, India. Electronic address: nishantchauhan.ranjan@gmail.com.

作者： Nishant Ranjan,Chauhan ^[1] ; Soumya,Kundu ^[2] ; Ramyasingh,Bal ^[3] ; Diya,Chattopadhyay ^[4] ; Rinku,Sahu ^[5] ; Subhash,Mehto ^[4] ; Rina,Yadav ^[5] ; Sivaram,Krishna ^[5] ; Kautilya Kumar,Jena ^[4] ; Sameekshya,Satapathy ^[2] ; Anusha,Pv ^[2] ; Krushna C,Murmu ^[6] ; Bharati,Singh ^[7] ; Srinivas,Patnaik ^[8] ; Sarita,Jena ^[9] ; Krishnan H,Harshan ^[2] ; Gulam Hussain,Syed ^[7] ; Mohammed M,Idris ^[2] ; Punit,Prasad ^[6] ; Santosh,Chauhan ^[10]

作者单位： Cell Biology and Infectious Diseases Unit, Department of Infectious Disease Biology, Institute of Life Sciences, Bhubaneswar 751023, India. Electronic address: nishantchauhan.ranjan@gmail.com. ^[1] CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana 500007, India. ^[2] Cell Biology and Infectious Diseases Unit, Department of Infectious Disease Biology, Institute of Life Sciences, Bhubaneswar 751023, India; School of Biotechnology, KIIT University, Bhubaneswar, India. ^[3] Cell Biology and Infectious Diseases Unit, Department of Infectious Disease Biology, Institute of Life Sciences, Bhubaneswar 751023, India. ^[4] Cell Biology and Infectious Diseases Unit, Department of Infectious Disease Biology, Institute of Life Sciences, Bhubaneswar 751023, India; Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, India. ^[5] Epigenetic and Chromatin Biology Unit, Institute of Life Sciences, Bhubaneswar 751023, India. ^[6] Virus-Host Interactions Lab, Department of Infectious Disease Biology, Institute of Life Sciences, Bhubaneswar, Odisha, India. ^[7] School of Biotechnology, KIIT University, Bhubaneswar, India. ^[8] Experimental Animal Facility, Institute of Life Sciences, Bhubaneswar 751023, India. ^[9] Cell Biology and Infectious Diseases Unit, Department of Infectious Disease Biology, Institute of Life Sciences, Bhubaneswar 751023, India; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana 500007, India. Electronic address: schauhan@ccmb.res.in. ^[10]

关键词 CP: Immunology CP: Microbiology Delta IRGM Ifnar1 Irgm1 Omicron SARS-CoV-2 hACE2- K18 mice interferon response