首页> RNA (New York, N.Y.)> miR-7 is recruited to the high molecular weight RNA-induced silencing complex in CD8<sup>+</sup> T cells upon activation and suppresses IL-2 signaling.

miR-7 is recruited to the high molecular weight RNA-induced silencing complex in CD8<sup>+</sup> T cells upon activation and suppresses IL-2 signaling.

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第一作者： Matilda,Toivakka

第一单位： Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.

作者： Matilda,Toivakka ^[1] ; Katrina,Gordon ^[1] ; Sujai,Kumar ^[1] ; José Roberto,Bermudez-Barrientos ^[1] ; Cei,Abreu-Goodger ^[2] ; Rose,Zamoyska ^[3] ; Amy H,Buck ^[3]

作者单位： Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom. ^[1] Institute of Ecology & Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom. ^[2] Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom Rose.Zamoyska@ed.ac.uk a.buck@ed.ac.uk. ^[3]

关键词 CD8+ T cell IL-2 high molecular weight RISC miR-7 microRNA

医学主题词动物(Animals);RNA诱导沉默复合物(RNA-Induced Silencing Complex);白细胞介素2(Interleukin-2);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);分子量(Molecular Weight);微RNAs(MicroRNAs);哺乳动物(Mammals)

DOI 10.1261/rna.079030.121

PMID 37879863

发布时间 2024-12-10

基金项目

WT_/Wellcome Trust/United Kingdom

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