首页> Nature communications> Immune synapse formation promotes lipid peroxidation and MHC-I upregulation in licensed dendritic cells for efficient priming of CD8<sup>+</sup> T cells.

Immune synapse formation promotes lipid peroxidation and MHC-I upregulation in licensed dendritic cells for efficient priming of CD8<sup>+</sup> T cells.

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第一作者： Diego,Calzada-Fraile

第一单位： Centro Nacional de Investigaciones Cardiovasculares, 28029, Madrid, Spain.

作者： Diego,Calzada-Fraile ^[1] ; Salvador,Iborra ^[2] ; Marta,Ramírez-Huesca ^[1] ; Inmaculada,Jorge ^[3] ; Enrico,Dotta ^[4] ; Elena,Hernández-García ^[2] ; Noa,Martín-Cófreces ^[5] ; Estanislao,Nistal-Villán ^[6] ; Esteban,Veiga ^[7] ; Jesús,Vázquez ^[3] ; Giulia,Pasqual ^[8] ; Francisco,Sánchez-Madrid ^[9]

作者单位： Centro Nacional de Investigaciones Cardiovasculares, 28029, Madrid, Spain. ^[1] Department of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, 28040, Madrid, Spain. ^[2] Centro Nacional de Investigaciones Cardiovasculares, 28029, Madrid, Spain.;Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), 28029, Madrid, Spain. ^[3] Laboratory of Synthetic Immunology, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy. ^[4] Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), 28029, Madrid, Spain.;Dynamic Video Microscopy Unit, Immunology Department, Instituto de Investigación Sanitaria Hospital Universitario La Princesa, Universidad Autónoma de Madrid, 28006, Madrid, Spain. ^[5] Microbiology Section, Departamento CC, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad CEU San Pablo, Boadilla del Monte, 28668, Madrid, Spain. ^[6] Department of Molecular & Cellular Biology, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain. ^[7] Laboratory of Synthetic Immunology, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.;Veneto Institute of Oncology IOV-IRCCS, Padua, Italy. ^[8] Centro Nacional de Investigaciones Cardiovasculares, 28029, Madrid, Spain. fsmadrid@salud.madrid.org.;Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), 28029, Madrid, Spain. fsmadrid@salud.madrid.org.;Immunology Department, Instituto de Investigación Sanitaria Hospital Universitario La Princesa, Universidad Autónoma de Madrid, 28006, Madrid, Spain. fsmadrid@salud.madrid.org. ^[9]